Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

MANGANESE GLYCEROPHOSPHATE.

Questionable CAS 143007-66-3 / ASTRINGENT

Manganese Glycerophosphate is an essential trace element designed to enhance skin vitality. It functions as an antioxidant cofactor, supports the structural integrity of collagen, and offers anti-inflammatory benefits for a more resilient complexion.

Summary

Antioxidant Astringent Anti-inflammatory Collagen Support Cellular Metabolism Support

Science

Mechanism of Action

As a vital trace element, Manganese Glycerophosphate primarily acts as a cofactor for superoxide dismutase, a crucial endogenous antioxidant enzyme that effectively neutralizes harmful reactive oxygen species and free radicals, thereby mitigating premature aging and cellular damage. It also plays a role in fostering cellular metabolism, which is essential for skin repair and renewal processes. Furthermore, manganese contributes to the biosynthesis of collagen, a protein critical for maintaining skin's firmness and elasticity, and exhibits anti-inflammatory properties that can help soothe irritation and reduce redness, particularly benefiting sensitive or problematic skin conditions.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

The ingredient demonstrates stability, though proper packaging and storage are critical to protect it from environmental factors such as moisture and light. It is slightly soluble in water, practically insoluble in alcohol and 96% ethanol, and freely soluble in dilute mineral acids.

Conflicts

  • heat
  • light
  • strong oxidizing agents
  • bases
  • amines
  • reducing agents
  • acids
  • acid anhydrides

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

While recognized by the FDA as a 'NUTRIENT SUPPLEMENT' for food applications, Manganese Glycerophosphate carries hazard statements including 'Causes mild skin irritation' (H316) and 'Causes eye irritation' (H320). The EPA identifies it as a known human respiratory toxicant and reports toxic effects at moderate doses in animal studies, contrasting with Environment Canada's classification of it as not expected to be toxic or harmful. A comprehensive safety review by the CIR is currently unavailable.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
Yes Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

While offering potential benefits such as antioxidant protection, collagen support, and anti-inflammatory action for sensitive skin, the ingredient's classification as a mild skin irritant and lack of a comprehensive CIR safety review for cosmetic use necessitate cautious formulation and application.

Related

Similar Ingredients

Finding similar ingredients…