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Moumoujus

MANGANESE ASPARTATE.

Optional CAS 16351-10-3 / SKIN CONDITIONING

Manganese Aspartate is an essential trace element acting as a skin-conditioning agent. It supports vital enzymatic functions crucial for antioxidant defense, collagen synthesis, and maintaining skin health against environmental stressors. Its multifaceted benefits contribute to improved skin integrity and resilience.

Summary

Skin-Conditioning Agent

Science

Mechanism of Action

Manganese Aspartate supports skin health primarily by serving as an essential trace element and a cofactor for several key enzymes. It notably boosts the activity of superoxide dismutase (MnSOD), an intrinsic antioxidant enzyme that safeguards skin cells from oxidative stress induced by ultraviolet radiation and environmental pollutants, thereby helping to mitigate premature skin aging and cellular damage. Additionally, this compound is integral to the synthesis of proline and hydroxyproline, amino acids crucial for collagen formation, which enhances skin barrier integrity, improves elasticity, and supports wound healing. Manganese also confers anti-inflammatory benefits, potentially reducing redness and swelling associated with inflammatory skin conditions.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Manganese L-Aspartate is readily soluble in water, forming an aqueous solution that is weakly acidic. No specific optimal pH range for its stability in cosmetic formulations has been identified in current data.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Manganese Aspartate has not been assessed for cosmetic safety by the Cosmetic Ingredient Review (CIR) Expert Panel. EWG Skin Deep rates it with 'LOW' concerns for cancer, allergies, immunotoxicity, and use restrictions, but notes 'LOW_MODERATE' for developmental and reproductive toxicity, 'Strong evidence of human neurotoxicity' (moderate concern), and 'Non-reproductive organ system toxicity' (low concern). The European Food Safety Authority (EFSA) previously found manganese aspartate to be 'not of safety concern' for nutritional use in food supplements, provided established guidance levels (e.g., 4 mg Mn/day for the general population) were not exceeded.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Optional

Manganese Aspartate is a promising skin-conditioning agent with well-established antioxidant, collagen-supporting, and anti-inflammatory mechanisms, although direct topical clinical efficacy data for this specific form is currently limited.

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