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Moumoujus

MANGANESE ADENOSINE TRIPHOSPHATE.

Valuable CAS 56842-80-9 / ANTIOXIDANT, SKIN CONDITIONING

Manganese Adenosine Triphosphate is an advanced active ingredient engineered to revitalize skin by combining the robust antioxidant defense of manganese with the fundamental cellular energy of Adenosine Triphosphate (ATP). This synergistic complex is designed to protect against environmental damage, enhance skin's repair processes, and promote a youthful, hydrated complexion.

Summary

Antioxidant Skin Conditioning Anti-inflammatory Wound Healing Cell Energizing Collagen Booster Elastin Booster Hydration Enhancer Anti-aging Skin Regeneration Sebum Regulator Microcirculation Enhancer

Science

Mechanism of Action

This ingredient functions by delivering a dual-action benefit. Manganese, a crucial trace element, acts as a potent antioxidant, neutralizing damaging free radicals and supporting skin's inherent metabolic functions, including the critical process of collagen synthesis. It further offers anti-inflammatory benefits, effectively calming redness and irritation, and accelerating wound healing. Concurrently, Adenosine Triphosphate (ATP), the universal energy molecule of cells, fuels essential dermatological processes. These include the production of collagen and elastin for improved firmness, bolstering skin hydration by boosting hyaluronan synthases, and enhancing the skin's natural antioxidant defenses. ATP also plays a vital role in cell repair and renewal, targeting specific regeneration pathways like ADIPOR1, ultimately contributing to a visible reduction in aging signs, soothing inflammatory responses, optimizing microcirculation, and assisting in the regulation of sebum production.

Research

Clinical Evidence

Low confidence
Effective range 0.1–0.5%
Optimal

0.1%

Transparency

Dusting Analysis

Not commonly dusted

No information found to suggest this ingredient is commonly used at sub-effective concentrations for marketing claims.

The Formula

Formulation

Solubility
Water
Optimal pH 6.8 – 7.4
0 7 14

Stability

Adenosine Triphosphate (ATP) is stable in aqueous solutions within a pH range of 6.8 to 7.4; outside this range, it undergoes rapid hydrolysis. While a 50 mg/mL aqueous solution of Adenosine 5'-triphosphate disodium salt is mildly acidic (typically around pH 3.5), the final product pH should be adjusted to the optimal range for stability. ATP has metal-binding properties but remains functionally compatible when mixed with ingredients like peptides and niacinamide.

Synergies

  • Peptides
  • Niacinamide

Conflicts

  • Extreme pH levels (below 6.8 or above 7.4)

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While Manganese Adenosine Triphosphate itself has not been specifically reviewed by the CIR Expert Panel, related adenosine ingredients, including Adenosine Triphosphate, have been deemed safe for cosmetic use. General safety data for Manganese Adenosine Triphosphate (CAS 56842-80-9) indicates no GHS hazard classifications. Sensitization tests with a 15% Disodium Adenosine Triphosphate mixture showed no signs of sensitization, suggesting a low risk profile.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Manganese Adenosine Triphosphate is a valuable multi-functional ingredient that leverages the combined benefits of antioxidant protection, cellular energizing, and comprehensive skin regeneration, offering a wide array of benefits across all skin types with a low irritancy potential.

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