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MALUS DOMESTICA CALLUS CULTURE EXTRACT.

Valuable / HAIR CONDITIONING

Malus Domestica Callus Culture Extract, derived from the rare Uttwiler Spätlauber apple, is a biotechnologically advanced ingredient engineered to protect and vitalize skin stem cells. This extract is recognized for its capacity to delay cellular aging processes and promote a more youthful skin appearance through intrinsic cellular support.

Summary

Antioxidant Anti-aging Skin conditioning Humectant

Science

Mechanism of Action

This extract, particularly when formulated as a liposomal preparation such as PhytoCellTec™ Malus Domestica, functions by safeguarding the vitality and extending the longevity of skin's epidermal stem cells. It delivers epigenetic factors and essential metabolites crucial for cellular endurance, stimulating the production and increasing the lifespan of human skin stem cells. This action protects cells from damage and visibly diminishes wrinkles. Furthermore, it enhances the productivity and longevity of fibroblast cells, vital for collagen and elastin synthesis, thereby improving skin firmness, elasticity, and overall texture. Rich in antioxidants including flavonoids, polyphenols, and vitamin C, it provides protection against UV radiation, neutralizes harmful free radicals, and strengthens the skin's protective barrier to enhance moisture retention and resilience.

Research

Clinical Evidence

Medium confidence
Effective range 0.04–2%
Optimal

2%

Key findings

  1. 01 Demonstrated a 15% reduction in the intensity and depth of wrinkles over a four-week study in twenty women using PhytoCellTec Malus Domestica.
  2. 02 Increased the colony forming efficiency of epidermal stem cells by 92% in vitro.
  3. 03 Reduced hair loss by 34% after one month and 41% after two months when incorporated into a hair lotion (PhytoCellTec™ Malus Domestica).

Transparency

Dusting Analysis

Not commonly dusted

As an active ingredient with demonstrated efficacy at specific concentrations, Malus Domestica Callus Culture Extract is typically included at levels intended to deliver its biological benefits rather than as a minimal 'dusting'.

The Formula

Formulation

Solubility
Water
Optimal pH 3 – 5
0 7 14

Stability

The commercial ingredient PhytoCellTec™ Malus Domestica is a patented liposomal preparation, which indicates that its active components are encapsulated and stabilized within liposomes for improved delivery and stability. The extract itself is soluble in water but insoluble in oil.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel in 2015 determined that available data were insufficient to conclude on the safety of 'malus domestica (apple) stem extract' in cosmetic products. However, industry sources generally describe it as a natural and safe ingredient, typically well-tolerated by most skin types with rare side effects.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Malus Domestica Callus Culture Extract is a valuable ingredient, leveraging plant stem cell technology to enhance skin vitality, reduce visible signs of aging, and provide antioxidant protection, making it suitable for all skin types.

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