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Moumoujus

MAGNOLIA OBOVATA BARK EXTRACT.

Valuable CAS 223749-85-7 / SKIN CONDITIONING

Magnolia Obovata Bark Extract is a botanical active, rich in magnolol and honokiol, renowned for its potent antioxidant, anti-inflammatory, and antimicrobial properties. It actively works to protect skin from oxidative stress, reduce visible redness and irritation, and support overall skin health and elasticity.

Summary

Antioxidant Anti-inflammatory Antimicrobial Skin Elasticity Enhancer Redness Reducer Moisture Restorer

Science

Mechanism of Action

The primary active compounds within Magnolia Obovata Bark Extract, magnolol and honokiol, confer its multi-functional benefits. They act as robust antioxidants, neutralizing free radicals to mitigate oxidative stress and premature cellular aging. Furthermore, they exert significant anti-inflammatory effects by inhibiting NF-κB, a crucial regulator of inflammatory pathways, thereby diminishing redness, swelling, and irritation. Its demonstrated antimicrobial activity against common skin pathogens such as *Staphylococcus aureus* and *Cutibacterium acnes* also supports clearer, healthier skin.

Research

Clinical Evidence

Medium confidence
Effective range 0.5–0.5%
Optimal

0.5%

Key findings

  1. 01 A controlled clinical study demonstrated that a cosmetic formulation containing 0.5% MAXnolia (a Magnolia-derived ingredient rich in magnolol and honokiol) significantly increased skin elasticity in the crow's feet area, improved moisture levels, reduced facial redness, and decreased signs of skin fatigue over 28 days of twice-daily application compared to a placebo.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 4 – 6.5
0 7 14

Stability

The extract is generally stable within a pH range of 4.0-6.5, particularly when formulated in a water/glycerin base. However, its primary active compounds, magnolol and honokiol, exhibit limited water solubility and benefit from incorporation into lecithin liposomes to enhance skin uptake and maintain stability, especially under alkaline conditions.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

While typically considered safe and well-tolerated, there are documented instances of skin sensitization and allergic contact dermatitis reported from related Magnolia species extracts (Magnolia officinalis bark extract) at topical concentrations between 0.05% and 0.5%. Dermal toxicity for Magnolia obovata bark extract specifically remains undetermined by official bodies.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

A multi-functional botanical ingredient offering significant antioxidant, anti-inflammatory, and antimicrobial benefits for diverse skin concerns, though potential for sensitization requires careful formulation.

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