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MAGNESIUM PCA.

Valuable CAS 5819-47-6 / HUMECTANT, SKIN CONDITIONING

Magnesium PCA is a bio-chelated compound that combines essential magnesium with pyrrolidone carboxylic acid, a key component of the skin's Natural Moisturizing Factor. This synergistic molecule delivers comprehensive hydration by attracting and retaining moisture, while also strengthening the skin barrier and supporting vital cellular functions.

Humectant Skin Conditioning Cellular Regenerator Collagen & Elastin Booster Anti-inflammatory Antimicrobial Barrier Support Sebum Regulator

Science

Operating as a sophisticated humectant, Magnesium PCA effectively draws and binds water within the stratum corneum, significantly boosting skin hydration and promoting a plump appearance. It plays a crucial role in reinforcing the skin's protective barrier and shielding the epidermis from environmental aggressors. By integrating into the skin's energy metabolism, it stimulates cellular regeneration, helping to diminish signs of fatigue. This active also encourages the synthesis of collagen and elastin, contributing to a smoother skin texture and a reduction in visible lines. Furthermore, its inherent anti-inflammatory and antimicrobial qualities can alleviate redness associated with acne and assist in balancing oil production. The PCA component facilitates enhanced magnesium penetration and collaborates with the skin's aquaporins, optimizing moisture retention and overall skin balance.


Research

Medium confidence
Effective range 0.5–3%
Optimal

N/A

Key findings

  1. 01 Magnesium ions have been observed to enhance skin hydration within the stratum corneum.
  2. 02 Recommended for its efficacy in humectancy, skin conditioning, promoting cellular regeneration, stimulating collagen and elastin production, and offering anti-acne benefits at concentrations ranging from 0.5% to 3% in cosmetic formulations.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Conflicts

  • N-nitrosating agents

Safety

CIR Status
Safe as used
Max tested
0.18%
Sensitization risk Low

The Cosmetic Ingredient Review Expert Panel concluded that Magnesium PCA, and other PCA salts, are safe for use in cosmetic formulations, based on products surveyed at concentrations up to 0.18%. It is explicitly advised not to use Magnesium PCA in products containing N-nitrosating agents.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Magnesium PCA is a versatile and valuable ingredient, offering multi-level hydration, anti-aging benefits, and barrier support across all skin types, with a low risk of irritation or comedogenicity, provided it's formulated without N-nitrosating agents.


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