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Moumoujus

MAGNESIUM ACETATE.

Valuable CAS 142-72-3 / BUFFERING

Magnesium Acetate, a source of vital magnesium ions, is a versatile ingredient that actively supports skin health by aiding cell repair, enhancing barrier function, and providing essential hydration. It also helps to calm inflammation and protect against environmental stressors.

Summary

Cell Repair Regeneration Anti-inflammatory Barrier Strengthening Hydration Antioxidant Collagen Production Support Hyperpigmentation Reduction Support Wound Healing Support

Science

Mechanism of Action

As a donor of magnesium ions, Magnesium Acetate significantly supports cellular health. It promotes the repair and regeneration of skin cells, contributing to the synthesis of collagen and the formation of new epidermal cells. This ingredient effectively modulates inflammatory pathways, which helps to alleviate redness and irritation associated with conditions such as acne, eczema, and rosacea. Furthermore, it reinforces the skin's natural barrier, optimizing hydration levels and mitigating trans-epidermal water loss (TEWL). Magnesium also offers protection against oxidative stress and can help address concerns like hyperpigmentation. In the context of wound healing, magnesium ions (specifically from MgCl2 and MgSO4, which release magnesium ions) have been observed to inhibit epidermal differentiation, facilitate cell migration via the MEK/ERK/MMP7 pathway, and stimulate hyaluronic acid synthesis within epidermal keratinocytes.

Research

Clinical Evidence

Medium confidence
Effective range 2–2%
Optimal

2%

Key findings

  1. 01 Topical application of a 2% Magnesium cream significantly improved diaper dermatitis and diaper rash in children.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 6 – 9
0 7 14

Stability

Magnesium Acetate is hygroscopic, readily absorbing atmospheric moisture, necessitating storage away from water. Its tetrahydrate form is well-suited for water-based formulations, whereas the anhydrous form is preferable for lower-moisture content systems. In topical compositions, maintaining magnesium salts in a completely dissolved state is crucial for optimal chemical interaction with the skin and to prevent potential solid deposits.

Conflicts

  • strong oxidizers

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) expert panel has determined Magnesium Acetate to be safe for use in cosmetics at reported concentrations, with a health hazard rating of zero. While generally well-tolerated, direct skin exposure may lead to mild irritation in some individuals. This ingredient is incompatible with strong oxidizing agents.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Magnesium Acetate is a valuable ingredient, offering broad benefits for skin health, including cellular repair, enhanced hydration, and inflammation reduction, making it suitable for a wide range of skin types and concerns.

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