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Moumoujus

MACLURA POMIFERA FRUIT EXTRACT.

Valuable CAS - / SKIN CONDITIONING

Maclura Pomifera Fruit Extract, derived from Osage orange, is a multifaceted skincare ingredient recognized for its robust antioxidant, anti-aging, and hydrating capabilities. Rich in beneficial isoflavonoids, it helps protect the skin while visibly improving its texture and appearance across various skin types.

Summary

Antioxidant Soothing Antimicrobial Astringent Anti-aging Hydrating

Science

Mechanism of Action

This extract is concentrated with prenylated isoflavonoids, including osajin and pomiferin, which are pivotal for its efficacy. These compounds exert significant antioxidant activity by neutralizing reactive oxygen species (ROS) and mitigating oxidative stress. It demonstrates anti-aging actions through the inhibition of key enzymes such as hyaluronidase, collagenase, and elastase, which degrade skin's structural components. Furthermore, its isoflavones are suggested to elevate the expression of collagen, elastin, and fibrillin, potentially comparable to or superior to retinol at equivalent concentrations. The extract also possesses anti-inflammatory and antimicrobial properties, effective against various Gram-positive bacteria, and has been shown in vivo to enhance skin hydration and calm irritation.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vivo skin tests demonstrated safety for topical use, increasing skin hydration and reducing irritation under occlusion.
  2. 02 Showed anti-aging potential by inhibiting hyaluronidase, collagenase, and elastase enzymes.
  3. 03 Exhibited good antioxidant activity.
  4. 04 Isoflavones from Maclura are suggested to increase collagen, elastin, and fibrillin expression, potentially surpassing retinol at similar concentrations.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

The extraction process of active compounds from Maclura pomifera can be challenging due to the adhesive nature of its compounds, potentially leading to high losses and low extraction yields during the condensation stage.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While specific CIR, SCCS, or FDA safety assessment reports are not available for Maclura Pomifera Fruit Extract, in vivo skin tests have confirmed its safety for topical application. These tests specifically noted an an increase in skin hydration and a reduction in irritation under occlusion, suggesting a well-tolerated profile.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

A valuable multi-functional ingredient, Maclura Pomifera Fruit Extract offers significant antioxidant, anti-aging, and hydrating benefits with a low risk of irritation, making it suitable for a wide range of skin types.

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