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Ingredient directory

Machilus Odoratissima Bark Extract

Machilus Odoratissima Bark Extract is a botanical ingredient rich in diverse phytochemicals, notably demonstrating significant antioxidant capabilities through free radical scavenging. It also exhibits targeted antibacterial properties against Staphylococcus aureus, indicating its potential for skin health applications.

Directory entry · Individual source review pending

This profile is awaiting an individual source review. Treat its ratings, dose estimates and compatibility labels as provisional; they are not medical advice or proof of a finished product’s effects.

Antioxidant Skin-Conditioning Agent Antibacterial

Science

Mechanism of Action

This extract functions by delivering a spectrum of phytochemicals, including terpenoids, tannins, and phenolic compounds, which collectively contribute to its biological activity. Its primary mechanisms involve neutralizing harmful free radicals, thereby providing antioxidant protection, and inhibiting the growth of specific bacteria like Staphylococcus aureus.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In an in vitro study, the methanol extract exhibited high free radical scavenging activity, demonstrating an IC50 of 3.37 µg/ml.
  2. 02 The extract also displayed dose-dependent antibacterial activity specifically against Staphylococcus aureus in laboratory settings.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

The extraction and defatting processes suggest the presence of both polar and non-polar compounds, indicating potential stability across various formulation types.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Machilus Odoratissima Bark Extract has not undergone specific safety reviews by CIR, SCCS, or FDA, and is listed as 'Not rated' by Paula's Choice. While a related species, Machilus Thunbergii Bark Extract, generally has a good safety profile, some individuals, particularly those with sensitive skin, may experience allergic reactions such as rashes or redness, leading regulatory authorities to recommend a patch test for related extracts.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Machilus Odoratissima Bark Extract presents valuable antioxidant and antibacterial properties observed in vitro; however, comprehensive human clinical safety data and precise formulation guidelines are currently limited for this specific species.

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