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Moumoujus

MACHILUS JAPONICA BRANCH/LEAF EXTRACT.

Valuable / SKIN PROTECTING

Machilus Japonica Branch/Leaf Extract is a botanical ingredient recognized for its multifunctional properties. It offers antioxidant protection against free radicals, contributes to skin hydration, and provides soothing benefits to reduce inflammation and redness. Furthermore, studies indicate its antimicrobial activity against certain bacteria and yeast.

Summary

Antioxidant Moisturizing Soothing Anti-inflammatory Antimicrobial

Science

Mechanism of Action

This extract works by mitigating oxidative stress through free radical scavenging, thereby protecting skin cells. Its inherent moisturizing capabilities aid in enhancing skin hydration and elasticity. The presence of specific compounds, such as lignans, contributes to its anti-inflammatory action by inhibiting superoxide anion generation and elastase release in neutrophils. The essential oil component also exhibits antimicrobial effects, suppressing the growth of Gram-positive bacteria and yeast.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Machilus japonica leaf essential oil demonstrated antioxidant activity with an IC50 of 51.8 µg/mL in a DPPH free radical scavenging assay.
  2. 02 The essential oil from Machilus japonica leaves showed strong growth inhibition against Gram-positive bacteria and yeast, with MIC values ranging from 16.12-32.25 µg/mL.
  3. 03 Isolated lignans from Machilus japonica var. kusanoi leaves, including (+)-eudesmin and (+)-pinoresinol, potently inhibited superoxide anion generation in human neutrophils with IC50 values ranging from 2.23 ± 0.92 µM to 8.71 ± 0.74 µM.

Transparency

Dusting Analysis

Not commonly dusted

There is no specific data indicating that Machilus Japonica Branch/Leaf Extract is commonly dusted in cosmetic formulations.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

While the Cosmetic Ingredient Review (CIR) has not specifically evaluated Machilus Japonica Branch/Leaf Extract, a related ingredient, Machilus Thunbergii bark extract, is generally considered safe. However, individuals with sensitive skin should exercise caution as allergic reactions such as rashes or redness are possible, and a skin patch test is recommended by some regulatory bodies.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Machilus Japonica Branch/Leaf Extract is a valuable botanical ingredient offering multi-faceted benefits, including antioxidant protection, hydration, soothing effects, and antimicrobial properties, supported by promising in vitro research.

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