Science
Mechanism of Action
As a dipeptide, Lysyl Ornithine supports the skin's structural integrity, contributing to its hydration, texture, and resilience. Its key component, Ornithine, is understood to activate the transcription factor HIF-1α, which can lead to a 'lipofilling-like' effect by potentially increasing fatty tissue volume. This action may visibly reduce the appearance of deep wrinkles, such as nasolabial folds. Furthermore, Ornithine promotes cellular regeneration, aids in maintaining skin elasticity, minimizes the look of fine lines, and can reduce skin sensitivity by soothing irritations and redness. Ornithine metabolism also produces urea, which boosts skin moisturization, and putrescine, a regulator of cellular proliferation, while also potentially enhancing collagen synthesis.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Amino acids, including Lysyl Ornithine, generally demonstrate excellent stability and are compatible with a broad range of active substances.
Synergies
- hyaluronic acid
- peptides
- vitamins
Safety
Safety Profile
Lysyl Ornithine is recognized under INCI. Although a specific CIR assessment for Lysyl Ornithine is not available, European Union regulatory authorities acknowledge Ornithine as a safe and effective cosmetic ingredient. Studies on oral L-Ornithine indicate a high No Observed Adverse Effect Level (NOAEL) of 12,000 mg/person/day for oral administration, with no serious side effects for most individuals. No specific GHS hazard statements were found for Lysyl Ornithine.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Lysyl Ornithine presents valuable potential for skin plumping, anti-aging, and enhanced hydration, leveraging its dipeptide structure and the distinct mechanisms of its ornithine component, making it suitable for a wide array of skin types and product formulations.
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