Science
Mechanism of Action
This ingredient operates by activating the skin's innate immune cells, thereby enhancing defense mechanisms against environmental aggressors and inflammation. Beta-glucan stimulates collagen synthesis, which leads to improved skin texture and a reduction in the visibility of fine lines and wrinkles. Its humectant properties draw and lock moisture into the skin, preventing dehydration and bolstering the skin barrier. Furthermore, Beta-glucan acts as an antioxidant, neutralizing free radicals and promoting wound healing. The enzymatic component, Lysozyme, demonstrates increased production in the presence of beta-glucan, suggesting a synergistic immune-modulating role within the skin.
Research
Clinical Evidence
Medium confidence0.1%
Transparency
Dusting Analysis
No data available in the provided research to suggest Lysozyme Beta-Glucan is commonly 'dusted' at sub-efficacious percentages. The clinical efficacy observed at 0.1% indicates a functional concentration.
The Formula
Formulation
Stability
Beta-glucan is water-soluble. While its optimal production pH ranges from 3.0 to 6.5, with some fungal strains exhibiting higher yields in alkaline conditions, Lysozyme's maximum thermal stability is observed at pH 5.0. Its activity can be significantly compromised at higher temperatures and pH levels. Beta-glucan itself is susceptible to degradation from biodegradation, chemical processes, thermal stress, mechanical energy, and oxidative cleavage.
Synergies
- The interaction between beta-glucan and lysozyme, where beta-glucan stimulates lysozyme production, suggests a synergistic effect in enhancing skin's immune response and defense mechanisms.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has assessed Beta-Glucan (as part of microbial polysaccharide gums) and concluded its safety for cosmetic applications at current usage practices and concentrations. It is documented as non-toxic, non-irritating, and non-sensitizing to the skin, indicating a low safety risk profile.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Lysozyme Beta-Glucan is a valuable multifunctional ingredient, offering robust anti-aging, moisturizing, and immune-modulating benefits across all skin types with a favorable safety profile.
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References
Sources
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- betterwayhealth.com ↗
- clinikally.com ↗
- dermatoljournal.com ↗
- vibrantskinbar.com ↗
- researchgate.net ↗
- nih.gov ↗
- korelu.de ↗
- newbeauty.com ↗
- mdpi.com ↗
- cir-safety.org ↗
- specialchem.com ↗
- scirp.org ↗
- ukm.my ↗
- megazyme.com ↗