Science
Mechanism of Action
This extract operates through multiple pathways to enhance skin health. It exhibits antioxidant activity by inhibiting oxygen-favored reactions, thereby protecting cells from oxidative damage. Its anti-inflammatory properties stem from the inhibition of leukocytes, exudation, and key pro-inflammatory enzymes and mediators like MPO, ADA, and IL-1β. The extract effectively reduces sebum production by inhibiting both lipoxygenase activity and sebaceous lipogenesis, specifically via the LA and DHT pathways. Additionally, it aids in skin brightening by inhibiting tyrosinase activity, which contributes to its bleaching properties, and may offer anti-aging benefits by inhibiting MMP-1 activity, which helps mitigate the appearance of fine lines and improve skin firmness.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Topical application of a 5% Lotus corniculatus seed extract demonstrated an immediate and long-lasting reduction in sebum content and oily skin area. This effect was attributed to the reduction of sebaceous lipogenesis through both the LA and DHT pathways. No adverse reactions were reported during the study.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Formulations containing lotus leaf extract, such as cleansing creams and foam cleansers, have shown high stability. While a slight decrease in pH was observed at 25°C, the products maintained integrity without significant off-flavor, discoloration, or physical changes at higher temperatures (45°C and 65°C) and under sunlight exposure.
Safety
Safety Profile
The Government of Canada's August 2021 assessment concluded that Lotus corniculatus extract is not harmful to human health or the environment at typical cosmetic exposure levels. Although certain forms of the plant can produce cyanogenic glycosides that release hydrogen cyanide (HCN), the estimated safety margins for cyanide exposure from cosmetics were deemed sufficient. A clinical study utilizing 5% topical application of Lotus corniculatus seed extract reported no adverse reactions.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Lotus Corniculatus Leaf/Stem Extract is a valuable ingredient, offering comprehensive benefits from antioxidant protection and anti-inflammatory action to sebum regulation and skin brightening, making it suitable for a variety of skin types and concerns.
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