Science
Mechanism of Action
This extract actively reduces sebaceous lipogenesis by targeting key pathways, specifically those involving linoleic acid (LA) and dihydrotestosterone (DHT), which are critical for sebum synthesis. Additionally, it demonstrates robust antioxidant, anti-inflammatory, and immunostimulant activities, inhibiting pro-inflammatory enzymes and mediators such as myeloperoxidase (MPO), adenosine-deaminase (ADA), and interleukin-1 beta (IL-1β) to protect and soothe the skin.
Research
Clinical Evidence
Medium confidence5%
Transparency
Dusting Analysis
No data available to suggest this ingredient is commonly 'dusted' or has specific dusting thresholds for formulation.
The Formula
Formulation
Stability
While no explicit optimal pH range for formulation stability is defined, an analytical method involving alkali hydrolysis followed by pH adjustment to between 6 and 7 was used for flavonoids within the extract, suggesting potential stability in this neutral to slightly acidic range.
Safety
Safety Profile
The Government of Canada has assessed Lotus Corniculatus extract as not harmful to human health or the environment at typical exposure levels. It is important to note that some phenotypes of the plant contain cyanogenic glycosides which can release hydrogen cyanide (HCN). However, the overall risk in cosmetic products, even with a theoretical maximum HCN content of 0.5% (5000 µg/g dry weight), was deemed low. Toxicity can be mitigated through drying, and exposure from cosmetic products is primarily expected via inhalation, with a low potential for ingestion from products such as lip balms.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Lotus Corniculatus Leaf Cell Extract is a valuable ingredient, particularly for oily and breakout-prone skin, offering proven sebum reduction, robust antioxidant protection, and anti-inflammatory benefits with a low irritation risk.
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References
Sources