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Moumoujus

LITSEA JAPONICA BRANCH/LEAF EXTRACT.

Valuable / SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Litsea Japonica Branch/Leaf Extract is a botanical active recognized for its significant anti-inflammatory and antioxidant properties. This ingredient actively works to calm cellular inflammatory responses, making it highly beneficial for soothing and protecting sensitive or irritated skin types.

Summary

Anti-inflammatory Antioxidant Soothing Skin Conditioning

Science

Mechanism of Action

This extract primarily exerts its anti-inflammatory effects by significantly reducing the production of key pro-inflammatory cytokines, specifically interleukin-6, interleukin-8, and interleukin-1 beta. This mechanism is suggested to be linked to its antioxidant activity, which involves the inhibition of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) gene expression, both critical mediators in inflammatory pathways.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 An in vitro study demonstrated that Litsea japonica leaf extract dose-dependently suppressed lipopolysaccharide (LPS)-induced pro-inflammatory cytokine (IL-6 and IL-8) mRNA and protein expression in periodontal ligament fibroblasts without cytotoxicity. It also effectively inhibited interleukin-1 beta-induced pro-inflammatory cytokine production.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Extracts from Litsea species, including Litsea japonica, are typically soluble in polar solvents such as water, ethanol, and methanol. Ethanol is often highlighted for its effectiveness in extracting the most bioactive compounds, suggesting good stability in polar solvent systems.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

No specific safety assessments by major regulatory bodies such as the Cosmetic Ingredient Review (CIR), Scientific Committee on Consumer Safety (SCCS), or Food and Drug Administration (FDA) have been identified for Litsea Japonica Branch/Leaf Extract.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Litsea Japonica Branch/Leaf Extract is a valuable botanical ingredient, offering significant anti-inflammatory and antioxidant benefits to soothe and protect the skin, making it particularly beneficial for sensitive and reactive complexions.

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