Science
Mechanism of Action
LITHOPS PSEUDOTRUNCATELLA CALLUS LYSATE optimizes the skin's microenvironment and stimulates vitamin D synthesis within epidermal cells, leading to a strengthened, revitalized, and glowing appearance. It provides deep hydration to cutaneous layers, improves microcirculation and oxygenation, and refines skin tone and texture. Rich in biomimetic glycocalyx-derived glycoconjugates, organic acids, and polyphenols, it reinforces dermal structure, boosts deep water reserves, and offers robust antioxidant protection (capturing 42% of DPPH free radicals) alongside anti-aging benefits (inhibiting collagenase and lipid peroxidation by 82%).
Research
Clinical Evidence
High confidence1.5%
Key findings
- 01 A clinical evaluation on 40 volunteers over 56 days (double-blind, placebo-controlled, twice daily application of 1.5% concentration) demonstrated a 17% increase in skin dewiness, improved skin luminosity, and reduced oiliness versus placebo. This concentration significantly increased cheek volume by 1.95cm³ (3%) and up to 3.5cm³ (4%) compared to placebo, offering a dermal filler-like effect. It also prevented a decrease in skin hydration and significantly boosted water retention capacity, showing a 17% increase in Tissue Water Index (TWI) for deep skin hydration versus initial time.
- 02 In vitro tests revealed that LITHOPS PSEUDOTRUNCATELLA CALLUS LYSATE boosted fibroblast proliferation by 17% at a 0.01% concentration and by 26% at a 1% concentration.
Transparency
Dusting Analysis
No data available in the provided research to suggest this ingredient is commonly dusted or to establish specific dusting thresholds.
The Formula
Formulation
Stability
Optimal incorporation is during the cooling phase, specifically below 40ºC. Suggested use levels range from 1% to 3%.
Safety
Safety Profile
This ingredient has not been specifically reviewed by the Cosmetic Ingredient Review (CIR) or the Scientific Committee on Consumer Safety (SCCS). However, all cosmetic ingredients in the European Union are subject to stringent safety laws and rigorous product safety assessments. It was not listed in a 2010 CIR public notice concerning ingredients with no reported uses or insufficient data under FDA's Voluntary Cosmetics Reporting Program.
Your Skin
Skin Compatibility
Our Assessment
Verdict
With robust clinical data demonstrating significant improvements in deep hydration, dermal volume, and luminosity, LITHOPS PSEUDOTRUNCATELLA CALLUS LYSATE is a valuable ingredient for advanced revitalizing and anti-aging skincare formulations.
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