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LITHIUM SULFIDE.

Avoid CAS 12136-58-2 / DEPILATORY

Lithium sulfide (Li2S) is an inorganic compound characterized by its extreme reactivity with water, which results in the release of highly toxic hydrogen sulfide gas. It is not recognized or safe for use in precision skincare formulations due to its inherent dangers.

Science

Upon contact with moisture, lithium sulfide undergoes rapid hydrolysis, generating lithium hydroxide, a potent base, and highly poisonous hydrogen sulfide gas (H2S). While hydrogen sulfide theoretically possesses reducing properties similar to some dermatological sulfur derivatives, any potential skin benefits are purely speculative and are severely overshadowed by the compound's significant toxicity and instability on the skin.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

Lithium sulfide is not incorporated into cosmetic formulations. Its extreme reactivity with water and subsequent generation of highly toxic hydrogen sulfide gas deem it fundamentally unsafe and unsuitable for skin application.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Lithium sulfide presents as a deliquescent white to yellow crystalline powder that readily absorbs atmospheric moisture. This absorption initiates hydrolysis, leading to the liberation of highly toxic hydrogen sulfide gas. It exhibits high solubility in water and ethanol but reacts violently with acids. Due to its extreme reactivity in aqueous environments, establishing an optimal pH for cosmetic formulation stability is not feasible, and it requires strict storage under inert atmospheric conditions.

Conflicts

  • Water
  • Moisture
  • Acids (especially strong and dilute acids)
  • Oxidizing agents

Safety

CIR Status
Not reviewed
Pregnancy
Caution
Sensitization risk High

Lithium sulfide is considered unsafe and unsuitable for cosmetic application due to its vigorous reaction with water, producing highly toxic hydrogen sulfide gas. There is no evidence of regulatory approval for its safe use in skincare by bodies such as the FDA or SCCS. Furthermore, the classification of related lithium compounds (e.g., lithium carbonate, hydroxide, chloride) as Category 1A reproductive toxicants by the ECHA raises significant concerns about potential harm to fertility, unborn children, and breastfed children, implying a similar risk profile for lithium sulfide.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Due to its extreme reactivity with water, generation of highly toxic hydrogen sulfide gas, and complete lack of recognized safe use in skincare, lithium sulfide must be strictly avoided in all cosmetic formulations.


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