Science
Mechanism of Action
This ingredient functions as a robust antioxidant, efficiently neutralizing reactive oxygen species (ROS) and molecular radicals, similar to superoxide dismutase (SOD). It strategically inhibits key enzymes responsible for the degradation of collagen (collagenase), elastin (elastase), and hyaluronic acid (hyaluronidase), thereby preserving the skin's structural integrity and moisture. Furthermore, it stimulates the synthesis of collagen, contributes to melanin reduction via tyrosinase inhibition for potential brightening effects, and modulates inflammatory pathways by decreasing factors such as IL-6, TNF-a, iNOS, and COX-2.
Research
Clinical Evidence
Medium confidence1%
Key findings
- 01 A 1% solution of lychee seed powder demonstrated superior antioxidant properties compared to a 1% ascorbic acid solution.
- 02 Lychee Seed Extract Liquid (containing not less than 0.15% polyphenols) used at 1%-5% in cosmetic products showed significant antioxidant activity, wrinkle reduction, collagen stimulation, and inhibition of collagenase, elastase, and hyaluronidase.
- 03 Fermented lychee seed liquid demonstrated repair effects on UVA-damaged cells, increased Type I collagen (COL-1) and elastin (ELN), boosted total antioxidant capacity, and reduced reactive oxygen species (ROS), malondialdehyde (MDA), and inflammatory factors (IL-6, TNF-a, iNOS, COX-2).
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Optimal stability for Lychee Seed Extract Liquid is noted within a pH range of 5.0 to 7.0. The ingredient should be stored in cool, dry conditions with temperatures below 30°C to maintain its efficacy.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has not formally reviewed Litchi Chinensis Seed Powder. While studies on fermented lychee seed liquid indicated no irritation in chick embryo allantoic membrane eye stimulation and red blood cell hemolysis tests, suggesting a low irritancy potential for the extract form, comprehensive sensitization data for the powder form is not specifically available. No maximum concentration for cosmetic use is established.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Litchi Chinensis Seed Powder is a valuable active ingredient, offering potent antioxidant benefits and promising multifaceted anti-aging, collagen-boosting, and brightening effects suitable for most skin types.
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References
Sources