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Moumoujus

LIQUIDAMBAR FORMOSANA FRUIT EXTRACT.

Insufficient Data / SKIN CONDITIONING

Liquidambar Formosana Fruit Extract, derived from the Chinese Sweetgum tree, is a botanical ingredient recognized in traditional practices for its various therapeutic applications. It is now being explored in precision skincare for its potential skin conditioning benefits, stemming from a rich profile of active compounds.

Summary

Skin Conditioning Antioxidant Anti-inflammatory Antimicrobial

Science

Mechanism of Action

The biological activity of this fruit extract is attributed to its diverse phytochemical composition, including terpenoids, flavonoids, and phenolic acids. These compounds are known to contribute to antioxidant defense, helping to mitigate oxidative stress in the skin. Furthermore, laboratory investigations suggest the extract may modulate inflammatory pathways by inhibiting pro-inflammatory mediators and exhibit antimicrobial properties, thereby serving as a multifunctional skin conditioning agent.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro studies on HT-29 cells showed that certain fractions of Liquidambar formosana fruit extract (LLT) exhibited strong antioxidant activity. One specific fraction, LLT-M, demonstrated robust antioxidant effects with minimal cytotoxicity, while other fractions displayed significant cytotoxicity at concentrations ranging from 0.39 µg/mL to 100 µg/mL.
  2. 02 Closely related Liquidambar styraciflua fruit extracts also exhibited in vitro antioxidant activity, with IC50 values reported at 4.64 µg/mL (aqueous), 16.45 µg/mL (polysaccharide), and 3.67 µg/mL (ethanolic extracts).
  3. 03 An in vitro study found that the addition of 200 µg/mL of L. formosana extract increased cell viability by 50% in a cell culture model inhibiting the influenza A H1N1 virus.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) has not conducted a specific safety review for LIQUIDAMBAR FORMOSANA FRUIT EXTRACT. Consequently, its maximum safe concentration for cosmetic use has not been established. Paula's Choice indicates the ingredient is not yet rated by their team, suggesting further analysis may be pending.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While traditional uses and promising in vitro studies suggest antioxidant, anti-inflammatory, and antimicrobial properties, there is currently insufficient direct clinical data or established safety profiles for its precise efficacy and optimal concentration in topical skincare formulations.

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