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LINOLEAMIDOPROPYL PG-DIMONIUM CHLORIDE PHOSPHATE DIMETHICONE.

Valuable CAS 243662-49-9 / 179005-04-0 / HAIR CONDITIONING

LINOLEAMIDOPROPYL PG-DIMONIUM CHLORIDE PHOSPHATE DIMETHICONE is a sophisticated phospholipid complex engineered to biomimic the skin's natural lipids. It precisely delivers essential linoleic acid to skin and hair, acting as a highly substantive conditioning agent. This ingredient imparts a long-lasting, silky, and non-greasy feel, enhancing moisturization and reinforcing epidermal structure.

Summary

Skin conditioning Hair conditioning Moisturizing Surfactant Emollient Barrier support

Science

Mechanism of Action

This ingredient functions as a biomimetic phospholipid complex, designed to mimic naturally occurring phospholipids. It efficiently deposits essential fatty acids, specifically linoleic acid derived from safflower oil, onto the skin and hair. Its positively charged molecular structure allows for strong substantivity, forming vapor-permeable protective films that contribute to sustained conditioning, moisturization, and structural replenishment. It also exhibits mild surfactant properties.

Research

Clinical Evidence

Medium confidence
Effective range 0.1–3%
Optimal

N/A

Key findings

  1. 01 Typical usage levels for skin and hair conditioning are observed between 0.1% and 1.0%.
  2. 02 Recommended dosage ranges extend up to 3.0% for achieving enhanced hair and skin softness.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 3.5 – 7
0 7 14

Stability

This ingredient is water-soluble, enabling cold processing and the creation of clear final products. It serves as a formulation aid for traditional silicones and effectively delivers essential fatty acids without causing salting out when combined with anionic surfactants. To maintain optimal stability, processing temperatures should not exceed 80°C.

Synergies

  • Formulation aid for traditional silicones
  • Compatible with anionic surfactants (prevents salting out)

Conflicts

  • Avoid processing temperatures above 80°C

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that this ingredient, along with related dimethicone polymers, is safe for use in cosmetic formulations due to its large molecular weight limiting significant skin absorption. However, EWG lists moderate concerns regarding its persistence in the environment and limited anaerobic biodegradability. Some suspicions of reproductive toxicity and endocrine disruption have been noted based on animal studies and EU classifications, alongside high contamination concerns. Conversely, SkinSAFE designates this ingredient as 'Teen SAFE' and 'Baby SAFE', indicating it is free from common allergens and added potentially hormone-altering chemicals.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

LINOLEAMIDOPROPYL PG-DIMONIUM CHLORIDE PHOSPHATE DIMETHICONE is a valuable, biomimetic conditioning agent, offering significant moisturizing and barrier support benefits across all skin types, with a low irritancy and comedogenicity profile, and deemed safe by CIR.

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