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Moumoujus

LILIUM POLYPHYLLUM FLOWER EXTRACT.

Valuable / SKIN CONDITIONING

Lilium Polyphyllum Flower Extract is a botanical active, rich in phenolic compounds and flavonoids, recognized for its multifaceted benefits including antioxidant protection, anti-inflammatory action, and melanin regulation. It contributes to a more radiant and soothed skin appearance. This extract is derived from the petals of the Lilium polyphyllum plant.

Summary

Antioxidant Anti-inflammatory Skin Brightening Soothing Melanin Regulation Cell Membrane Stabilization

Science

Mechanism of Action

The extract's efficacy stems from a diverse profile of bioactive compounds, including phenolic acids, flavonoids, saponins, alkaloids, mucilaginous polysaccharides, and steroidal glycosides. These molecules deliver antioxidant effects by neutralizing free radicals and potentially absorbing UV radiation. Its anti-inflammatory properties are observed through the reduction of nitric oxide (NO) production and stabilization of cell membranes, with specific components like palmitic acid and methyl palmitate implicated. Furthermore, it inhibits tyrosinase, an enzyme critical for melanin synthesis, thereby assisting in preventing hyperpigmentation and promoting skin brightening. Traditional uses also suggest roles in soothing irritation, supporting wound healing, and offering mild antimicrobial benefits.

Research

Clinical Evidence

Medium confidence
Effective range 200–5000%
Optimal

N/A

Key findings

  1. 01 In vitro assessments at 200 µg/mL demonstrated anti-inflammatory activity comparable to a standard anti-inflammatory drug, evaluated via an albumin denaturation assay.
  2. 02 Concentrations between 500-5000 µg/mL showed dose-dependent antioxidant efficacy, with ethanol extracts potentially more potent than water extracts for some lily species. At 5000 µg/mL, the extract inhibited LPS-stimulated nitric oxide (NO) production, indicating anti-inflammatory action, and suppressed tyrosinase activity for skin brightening.
  3. 03 Various extracts (water, ethanol, DCM) ranging from 50-500 µg exhibited anti-inflammatory benefits by stabilizing human red blood cell membranes against hypotonicity-induced lysis, with water extract showing superior stabilization.
  4. 04 Further in vitro analyses revealed high phenolic content, offering DPPH radical-scavenging rates similar to green tea extracts, reinforcing its antioxidant properties.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Pregnancy
Caution
Sensitization risk Moderate

Safety data for Lilium polyphyllum in pregnancy is considered inadequate, and its use is not recommended for children under 12 without professional supervision. Rare instances of skin rash on contact have been reported for the plant in general.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Lilium Polyphyllum Flower Extract offers valuable antioxidant, anti-inflammatory, and brightening benefits through multiple mechanisms, supported by promising in vitro data, making it a versatile ingredient for diverse skin concerns.

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