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LILIUM PHILADELPHICUM FLOWER EXTRACT.

Valuable / FRAGRANCE

Lilium Philadelphicum Flower Extract is a multifaceted botanical ingredient celebrated for its comprehensive skin benefits. It effectively calms irritation and enhances hydration, promoting a supple complexion. Furthermore, it offers powerful antioxidant protection, anti-inflammatory effects, and contributes to a brighter, more even skin tone through its tyrosinase inhibiting and antimicrobial properties.

Antioxidant Soothing Moisturizer/Humectant Anti-inflammatory Antimicrobial Skin Brightening

Science

This extract functions by a multi-pronged approach to skin health. It delivers soothing relief by reducing redness and irritation, while actively promoting skin hydration for a plump, moisturized feel. Its antioxidant capacity, driven by free radical scavenging and UV absorption, helps defend against environmental damage. Furthermore, it modulates inflammatory responses by suppressing nitric oxide production and supports skin brightening through tyrosinase inhibition. The presence of diverse bioactive compounds, including phenols, flavonoids, and polysaccharides, also confers antimicrobial action against a range of bacteria and fungi.


Research

Medium confidence
Effective range 12.5 μg/mL–5000 μg/mL%
Optimal

N/A

Key findings

  1. 01 In vitro studies indicate potent antimicrobial activity, with Minimum Inhibitory Concentrations (MICs) as low as 12.5 μg/mL against Bacillus subtilis, 25 μg/mL against Acinetobacter bouvetii, and 50 μg/mL against Achromobacter xylosoxidans and Candida albicans (methanolic extracts).
  2. 02 Anti-inflammatory effects were observed through dose-dependent suppression of nitric oxide production, reaching higher efficacy at 5000 μg/mL in ethanol extracts.
  3. 03 Ethanolic extracts demonstrated concentration-dependent antioxidant activity between 500-5000 μg/mL (DPPH radical scavenging) and good tyrosinase inhibition potential for skin brightening (ethanolic and water extracts).
  4. 04 Cytotoxicity assessment in HepG2 cells showed up to 90% cell viability at a concentration of 50 μg/mL, suggesting good cellular tolerability.

Transparency

Not commonly dusted

The extract demonstrates multiple measurable bioactivities across a range of in vitro concentrations, suggesting it is utilized for its functional properties rather than solely for marketing claims. Specific dusting thresholds for cosmetic applications are not available in the provided data.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Safety

CIR Status
Not reviewed
Sensitization risk Low

No specific safety assessments from CIR (Cosmetic Ingredient Review) or SCCS (Scientific Committee on Consumer Safety) are available for Lilium philadelphicum flower extract. While some other lily species extracts have received approval for cosmetic use in regions like China, this does not directly apply to L. philadelphicum. In vitro cytotoxicity testing showed high cell viability (up to 90% at 50 μg/mL) in HepG2 cells, suggesting good tolerability at this concentration. INCIDecoder rates its irritancy as low.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Lilium Philadelphicum Flower Extract is a valuable botanical offering a wide array of benefits including antioxidant protection, anti-inflammatory action, hydration, and antimicrobial properties, making it suitable for diverse skin concerns despite limited human clinical data.


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