Science
Mechanism of Action
This extract derives its efficacy from a rich profile of phenolic acids, flavonoids, and polysaccharides, including specific components like kaempferol and quercetin glycosides. These compounds collectively inhibit COX-1 and COX-2 enzymes and lipid peroxidation, thereby exerting potent anti-inflammatory and antioxidant effects. Furthermore, it actively prevents tyrosinase activity, a crucial step in melanin synthesis, and reduces nitric oxide generation in inflamed cells, contributing to its skin-calming and brightening properties.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Demonstrated significant antioxidant activity in a concentration-dependent manner, particularly with ethanol extracts, across a range of 500-5000 µg/mL. This concentration range showed a linear correlation with antioxidant activities.
- 02 Exhibited anti-inflammatory effects by effectively preventing nitric oxide (NO) generation in inflamed RAW 264.7 macrophage cells within the 500-5000 µg/mL range, with higher efficacy at maximum concentration. It also reduced 40-50% viability of LPS-stimulated RAW264.7 cells.
- 03 Showed potential in inhibiting tyrosinase activity at various concentrations, which is critical for mitigating melanin accumulation and promoting an even skin tone.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
While formal CIR, SCCS, or FDA safety assessments are not available for this specific extract, lily extracts generally have approval from the China Food and Drug Administration for cosmetic applications. Broad patent analysis indicates a lack of reported side effects, and its inclusion as a fragrance ingredient by COSMILE Europe suggests compliance with cosmetic regulations for general use.
Your Skin
Skin Compatibility
Our Assessment
Verdict
LILIUM LONGIFLORUM FLOWER EXTRACT is a valuable botanical offering multi-faceted benefits, including robust antioxidant and anti-inflammatory action, alongside significant brightening and soothing properties, making it suitable for a wide range of precision skincare formulations.
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