Science
Mechanism of Action
This extract operates through several biological pathways; it is traditionally recognized for its antimelanogenic effects, contributing to skin brightening, and its ability to deeply hydrate the skin. Constituents found in related Ligusticum species exhibit antioxidant, anti-inflammatory, and anti-apoptotic properties. Furthermore, it may enhance local microcirculation and act as a permeation enhancer, potentially optimizing the absorption of other active ingredients.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 A 25% concentration of Ligusticum sinense hexane extract (LHE) demonstrated no local skin reaction, such as rash, swelling, or irritation, when applied to human skin.
- 02 Ligusticum sinense is externally used for skin whitening and hydration, with identified antimelanogenic components.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
While specific stability data for cosmetic formulations are not extensively documented, components like phthalides found in related Ligusticum volatile oils have shown stability in biological systems. General optimal pH range for cosmetic formulations remains to be fully elucidated.
Safety
Safety Profile
LIGUSTICUM SINENSE ROOT EXTRACT currently lacks formal review by CIR, SCCS, or FDA. However, a human study indicated no local skin irritation, rash, or swelling at a 25% concentration of its hexane extract. A related ingredient, 'Ligusticum Chuanxiong Root Extract,' is noted as 'Irritant Free' and 'Teen SAFE' by SkinSAFE, suggesting a favorable safety profile within the Ligusticum genus.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Ligusticum Sinense Root Extract is a valuable ingredient, traditionally revered for its skin brightening and hydrating capabilities, with promising antioxidant and anti-inflammatory potential, and a demonstrated low risk of irritation at specific concentrations.
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