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Moumoujus

LIGUSTICUM JEHOLENSE FLOWER/ROOT EXTRACT.

Insufficient Data CAS - / SKIN CONDITIONING

LIGUSTICUM JEHOLENSE FLOWER/ROOT EXTRACT is a botanical extract derived from the Gao-Ben plant, recognized for its potential anti-inflammatory and antioxidant properties. It is also noted for its ability to enhance skin penetration and may offer skin brightening benefits.

Summary

skin conditioning anti-inflammatory antioxidant skin penetration enhancer skin brightening

Science

Mechanism of Action

This extract possesses inherent anti-inflammatory and antioxidant capabilities, which can contribute to skin calming and protection against environmental stressors. Its essential oil has been observed to enhance the absorption of active components by subtly altering the stratum corneum barrier structure. Furthermore, research indicates vasorelaxant effects in isolated tissues, associated with modulation of K+ channels and extracellular Ca2+ entry, potentially supporting microcirculation. Related Ligusticum species exhibit similar benefits, including anti-apoptotic effects and contributions to hydration.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In an in vitro study on isolated rat aortic rings, a concentration of 500 μg/mL demonstrated a maximal concentration-dependent vasorelaxant effect.
  2. 02 The essential oil of Ligusticum jeholense was observed to enhance skin penetration by modifying the stratum corneum barrier, suggesting a potential role in improving the efficacy of other active ingredients and contributing to a 'whitening effect'.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel has not evaluated LIGUSTICUM JEHOLENSE FLOWER/ROOT EXTRACT for safety in cosmetic applications. Existing data do not provide sufficient information to establish its sensitization risk or a maximum safe concentration for use in finished products. One review source indicates 'no known benefits' due to lack of reviewed research.

Your Skin

Skin Compatibility

Yes Normal
No Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While preliminary research suggests anti-inflammatory, antioxidant, and penetration-enhancing potential, comprehensive human clinical efficacy and safety data for cosmetic use are currently insufficient, warranting further investigation.

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