Science
Mechanism of Action
Leuconostoc Ferment Lysate Filtrate primarily functions by secreting antimicrobial peptides and lactic acid, effectively inhibiting microbial growth to preserve cosmetic formulations. On the skin, it contributes to hydration and conditioning, balances the skin's pH, and supports a healthy microbiome by favoring beneficial bacteria while discouraging detrimental ones, which is particularly useful for managing acne-prone conditions.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
This ingredient maintains stability across a wide pH range from 3.0 to 8.0. It tolerates temperatures up to 60-70°C, but for optimal integration and to preserve its efficacy, it is recommended to incorporate it during the cooling phase of the formulation process, ideally below 40°C.
Conflicts
- Viscosity loss may be experienced when formulated in systems containing anionic, amphoteric, or nonionic surfactants, potentially necessitating the addition of a thickening agent.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel issued a final report on Leuconostoc/Radish Root Ferment Lysate Filtrate in June 2022. While a specific maximum safe concentration was not detailed, toxicity testing indicated non-sensitizing effects at 10% in aqueous solutions and 0.04% in an eyebrow gel. However, an in vitro phototoxicity assay demonstrated a significant reduction in cell viability (≥20%) at an 11% concentration.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Leuconostoc Ferment Lysate Filtrate is a valuable multi-functional ingredient providing natural preservation, hydration, and microbiome support with a low risk of irritation across all skin types.
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