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Moumoujus

LEUCOJUM AESTIVUM BULB EXTRACT.

Valuable CAS - / SKIN PROTECTING

Leucojum Aestivum Bulb Extract is a multi-functional botanical ingredient prized for its significant anti-aging, antioxidant, and skin-brightening capabilities. It precisely targets the appearance of dynamic wrinkles by modulating muscle contractions, while simultaneously bolstering the skin's defense against oxidative stress and reducing the visibility of age spots.

Summary

anti-aging antioxidant skin-conditioning muscle relaxant wrinkle reduction skin lightening melanin inhibition

Science

Mechanism of Action

This extract functions through a multifaceted approach to skin rejuvenation. Its primary action involves inhibiting the release of acetylcholine, a neurotransmitter crucial for muscle contraction, thereby relaxing facial muscles responsible for dynamic wrinkles in a manner comparable to neurotoxin treatments. Concurrently, it fortifies the skin's endogenous antioxidant system by upregulating the expression of Superoxide Dismutase (SOD), mitigating oxidative damage. Furthermore, it appears to slow the proliferation rates of melanocytes and keratinocytes, contributing to a reduction in melanin synthesis, which can visibly diminish age spots and promote overall cellular longevity. This biological transfer of the plant's dormancy state is believed to instill a rejuvenating 'beauty sleep' effect on skin cells.

Research

Clinical Evidence

High confidence
Effective range 0.15–2%
Optimal

N/A

Key findings

  1. 01 Increased the expression of the antioxidant enzyme MnSOD in keratinocytes by 20% (p < 0.05).
  2. 02 Blocked muscular contraction frequency in vitro at 2, 6, and 24 hours after application, with a lasting effect observed 1 hour after removal.
  3. 03 Within a composition, showed a smoothing and anti-wrinkle effect on micro-relief furrows and medium depth wrinkles, demonstrating superior efficacy compared to a control without the extract.
  4. 04 Reduced wrinkle depth and surface roughness, and improved skin smoothness and elasticity by inhibiting acetylcholine release, analogous to Botox.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 4.5 – 6.5
0 7 14

Stability

The extract maintains stability and optimal activity within an approximate pH range of 4.50 to 6.50.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While formal review by CIR or SCCS is pending, in vitro and patch tests indicate the extract is non-irritating to the skin after 48 hours. It is rated 'Irritant Free' by SkinSAFE and 'LOW' for Allergies & Immunotoxicity by EWG, suggesting a favorable safety profile for topical use.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Leucojum Aestivum Bulb Extract is a valuable, multifaceted ingredient offering significant anti-aging benefits through muscle relaxation, antioxidant protection, and pigmentation modulation with a low irritation potential.

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