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Moumoujus

LESPEDEZA CAPITATA FLOWER/LEAF/STEM EXTRACT.

Valuable CAS 84837-05-8 / SKIN CONDITIONING

Lespedeza Capitata Flower/Leaf/Stem Extract primarily functions as a comprehensive skin conditioning and protective agent, forming a barrier to enhance moisture retention and defend against external stressors. Beyond its benefits for maintaining healthy skin, it also offers specialized advantages for scalp health, including addressing concerns such as hair loss and seborrheic conditions.

Summary

Skin conditioning Skin protectant Moisturizing Anti-hair loss Scalp conditioning

Science

Mechanism of Action

This extract operates as a skin conditioning and protectant by assisting in the formation of a protective film on the skin's surface. This barrier function is critical for minimizing trans-epidermal water loss, effectively locking in moisture, and shielding the skin from various environmental aggressors. For scalp applications, clinical findings indicate its capacity to inhibit 5α-reductase activity and suppress the synthesis and release of Dickkopf-related protein 1 (DKK1) from dermal papilla cells. These actions are associated with delaying and preventing hair loss, extending the hair's life cycle, and proving beneficial in managing scalp conditions like seborrhea, seborrheic dermatitis, and erythema.

Research

Clinical Evidence

Medium confidence
Effective range 0.0001–2%
Optimal

N/A

Key findings

  1. 01 Clinical data derived from patent applications WO2020020791A1 and US20210169960A1 demonstrates that Lespedeza Capitata Flower/Leaf/Stem Extract, within a concentration range of 0.0001% to 2% (with a preferred range of 0.001% to 1%) of dry extract by weight, can effectively inhibit 5α-reductase activity. This mechanism also suppresses the synthesis and release of DKK1 by dermal papilla cells, which is linked to delaying and preventing hair loss, extending the hair life cycle, and treating scalp conditions such as seborrhea, seborrheic dermatitis, and erythema.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Side effects and adverse reactions are generally uncommon. However, a patch test is always recommended prior to widespread usage to ensure there is no adverse reaction. There is a possibility of allergic reactions in individuals sensitive to the Fabaceae plant family.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

This versatile botanical extract is a valuable component for both skincare and haircare formulations, offering robust skin conditioning, protective qualities, and targeted benefits for scalp health and hair loss prevention.

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