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Moumoujus

LESPEDEZA CAPITATA EXTRACT.

Valuable CAS 84837-05-8 / SKIN CONDITIONING

Lespedeza Capitata Extract is a botanical active specifically developed to mitigate the impact of contemporary stressors like blue light on skin. It precisely targets the skin's intrinsic circadian rhythms, revitalizing cellular processes to enhance complexion, boost radiance, and strengthen natural defense mechanisms.

Summary

Circadian Rhythm Regulator Blue Light Protector Antioxidant Skin Conditioner Skin Protector Radiance Enhancer Anti-Fatigue Moisturizing Agent

Science

Mechanism of Action

This extract precisely rebalances the skin's biological clock by resynchronizing circadian genes (Bmal-1, Per, Cry) whose expression is often disrupted by stress, jet lag, or blue light. Rich in flavonoids such as carlinoside and isoscaptoside, it strengthens the skin barrier and optimizes chronobiological processes, including nocturnal aquaporin-3 activity for improved moisturization and collagen synthesis. This action leads to a younger, fresher complexion, reduced skin fatigue, and robust antioxidant protection, while also forming a protective barrier to lock in moisture.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro experiments demonstrated significant efficacy against blue light-induced skin damage and the re-establishment of dysregulated circadian rhythms, leading to resynchronization of Bmal-1, Per, and Cry genes. This also regulated aquaporin 3 and Nrf2 pathways, resulting in enhanced skin radiance, improved complexion, enhanced biorhythms, and antioxidant activity.
  2. 02 Clinically proven to visibly reduce the appearance of skin fatigue in women exposed to artificial blue light from screens. It also progressively improved skin complexion and radiance in women with deregulated circadian rhythms.
  3. 03 Moderate free radical scavenging activity was observed in vitro, with an IC50 of 87.3 ± 5.6 µg/mL in the DPPH assay.
  4. 04 Moderate free radical scavenging activity was observed in vitro, with an IC50 of 56.8 ± 3.2 µg/mL in the ABTS assay.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has not conducted a safety assessment for Lespedeza Capitata Extract as a cosmetic ingredient. Comprehensive data on oral, parenteral, dermal, and inhalation toxicity is generally 'not determined' by major regulatory bodies like SCCS or FDA for cosmetic use. However, current data suggests a low irritancy potential.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Lespedeza Capitata Extract is a valuable botanical ingredient, offering precision benefits for skin health by addressing modern concerns such as blue light exposure and circadian rhythm disruption, contributing to a revitalized and radiant complexion.

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