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Moumoujus

LEPTADENIA RETICULATA LEAF POWDER.

Insufficient Data CAS 92457-15-3 / SKIN CONDITIONING

Leptadenia Reticulata Leaf Powder is a botanical ingredient, traditionally valued for its skin-conditioning attributes and rich in diverse bioactive compounds. Research suggests its potential for anti-inflammatory, antioxidant, and antimicrobial effects, making it a promising component for targeted skincare formulations. It is specifically compatible with normal, dry, and sensitive skin types.

Summary

Skin Conditioning Anti-inflammatory Antioxidant Antibacterial Antifungal Wound Healing Support

Science

Mechanism of Action

This ingredient functions through its complex profile of bioactive compounds, including flavonoids, phenolic acids, saponins, and triterpenoids. These constituents collectively contribute to its anti-inflammatory action, which can help alleviate skin redness and swelling. Its antioxidant properties provide protection against environmental stressors, while demonstrated antibacterial and antifungal activities may support a healthy skin microbiome. Traditionally, the plant is also recognized for its role in wound healing.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH ≥5.88
0 7 14

Stability

A dried aqueous extract of the whole plant exhibited a pH of 5.88, which may indicate an optimal pH for its stability. The ingredient primarily shows water solubility, with water-soluble extractive content reported at no less than 56.00% W/W, compared to methanol-soluble at no less than 28.00% W/W and hexane-soluble at no less than 2.00% W/W. Specific stability data for cosmetic formulations of the leaf powder is not readily available.

Safety

Safety Profile

CIR Status
Not yet reviewed, but prioritized for 2024 assessment.
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) has added Leptadenia Reticulata to its 2024 Final Priority List for safety assessment. While not specifically for topical use, oral administration of an aqueous extract and leptaden was tolerated up to 3.125 g/kg in rats, though higher oral doses were associated with increased mortality. It has been described as a safe herbal drug for some traditional internal uses without reported toxic side effects. The ingredient is not recommended for fragrance or flavor applications.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

Leptadenia Reticulata Leaf Powder demonstrates promising in-vitro and animal data for anti-inflammatory, antioxidant, and antimicrobial effects relevant to skin health, but further human topical clinical studies and a formal safety review are required for a definitive assessment of its precise cosmetic application.

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