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Moumoujus

LEPTADENIA RETICULATA LEAF EXTRACT.

Valuable CAS 92457-15-3 / SKIN CONDITIONING

Leptadenia Reticulata Leaf Extract is a botanical ingredient recognized for its diverse beneficial properties, primarily functioning as a skin conditioning agent. It offers antioxidant, antimicrobial, and anti-inflammatory effects, contributing to overall skin health and revitalization. Its multi-faceted action makes it a promising component for various skincare formulations.

Summary

skin conditioning antioxidant antimicrobial anti-inflammatory wound healing revitalizing

Science

Mechanism of Action

This extract's efficacy stems from a rich profile of bioactive compounds, including α-amyrin, β-amyrin, ferulic acid, luteolin, diosmetin, rutin, and β-sitosterol. These constituents work synergistically to combat oxidative stress, provide broad-spectrum antimicrobial defense against bacteria and fungi, reduce inflammation, and support natural wound healing processes, thereby promoting revitalized and rejuvenated skin.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Ethanolic extracts exhibited potent antifungal activity against various tested fungal strains, suggesting a role in combating skin fungal issues.
  2. 02 Silver nanoparticles synthesized using the leaf extract demonstrated antibacterial activities against pathogenic microorganisms, including E. coli and B. subtilis, with inhibition zones increasing proportionally to concentration.
  3. 03 General findings confirm significant antioxidant and antimicrobial activity of ethanolic extracts, supporting its potential for skin protection and purity.
  4. 04 Demonstrated immunomodulatory and antioxidant activity, increasing antioxidant enzyme levels (GSH, SOD, CAT) and decreasing lipid peroxidation (LPO) in immunosuppressed subjects, indicating systemic protective effects.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Stability

A dried aqueous extract (Ghana) was measured at a pH of 5.88. However, specific optimal pH ranges for maintaining stability and efficacy within cosmetic formulations have not been definitively identified.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

Formal safety assessments by regulatory bodies such as the Cosmetic Ingredient Review (CIR) or the Scientific Committee on Consumer Safety (SCCS) for cosmetic applications are not available. Oral toxicity studies in rats indicated the extract could be tolerated safely up to 3.125 g/kg, though this data is not directly transferable to topical cosmetic safety profiles.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Leptadenia Reticulata Leaf Extract is a valuable botanical offering antioxidant, antimicrobial, and skin conditioning benefits, with promising potential awaiting further human topical efficacy studies to solidify its precise impact on skin health.

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