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LEPIDIUM MEYENII ROOT POWDER.

Valuable / HUMECTANT

Lepidium Meyenii Root Powder, derived from the Maca plant, is a multi-functional botanical ingredient rich in bioactive compounds. It demonstrates significant antioxidant and anti-inflammatory properties, alongside potential anti-aging and skin brightening benefits. This ingredient supports skin vitality and a more even, radiant complexion.

Summary

Antioxidant Skin-Conditioning Humectant Anti-inflammatory Anti-aging Skin brightening

Science

Mechanism of Action

This ingredient's antioxidant capacity is attributed to a rich profile of polysaccharides, macaenes, macamides, glucosinolates, and phenolic compounds, including flavonoids and epicatechin. Its anti-inflammatory action, particularly with fermented extracts, is mediated by a reduction in nitric oxide (NO) secretion. Anti-melanogenic effects involve the inhibition of tyrosinase activity and melanin synthesis, coupled with suppression of MITF, tyrosinase, and TRP-2 mRNA expression. Furthermore, it promotes anti-aging by stimulating fibroblast synthesis, enhancing collagen and protein production, boosting tissular adhesion, and increasing the synthesis of extracellular matrix (ECM) components like integrins and collagen IV, contributing to improved skin suppleness and elasticity.

Research

Clinical Evidence

Medium confidence
Effective range 5–10%
Optimal

N/A

Key findings

  1. 01 In vitro studies utilizing 5% and 10% fermented maca root extracts demonstrated a reduction in nitric oxide (NO) secretion in RAW 264.7 cells, indicating anti-inflammatory efficacy.
  2. 02 In vitro studies at 10% fermented maca root extracts inhibited tyrosinase activity, melanin synthesis, and melanogenesis by suppressing MITF, tyrosinase, and TRP-2 mRNA expression in B16F10 cells, suggesting anti-melanogenic and skin-whitening potential.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Fermentation with Lactobacillus strains has been shown to enhance its anti-inflammatory and anti-melanogenic effects, potentially improving ingredient stability and efficacy.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

While the Food and Agriculture Organization (FAO) recommended Maca as a safe edible food in 1992 and USP-NF evaluations for dietary ingredients have reported no serious adverse events for single-ingredient maca products, topical dermal toxicity remains undetermined. Neither the Cosmetic Ingredient Review (CIR) nor the Scientific Committee on Consumer Safety (SCCS) has explicitly reviewed Lepidium Meyenii Root Powder for topical cosmetic use. Oral consumption has rarely been associated with transient adverse effects, but these are not directly extrapolable to topical application.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Lepidium Meyenii Root Powder is a valuable multi-functional ingredient demonstrating in vitro antioxidant, anti-inflammatory, anti-aging, and skin-brightening properties, particularly when processed via fermentation.

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