LEONURUS SIBIRICUS/(ERIOBOTRYA JAPONICA/MORUS ALBA) LEAF EXTRACT.

The composite extract functions through several synergistic pathways. Leonurus Sibiricus provides significant antioxidant capacity by reducing intracellular reactive oxygen species (ROS) and offering protection against UVB-induced cellular damage. Eriobotrya Japonica actively combats inflammation by inhibiting key mediators such as nitric oxide (NO), iNOS, COX-2, TNF-α, and IL-6, primarily by attenuating NF-κB activation. It also scavenges free radicals due to its rich polyphenol and quercetin content, inhibits melanin synthesis for brightening, and supports skin structure by reducing the activity of collagenase and hyaluronidase enzymes while stimulating collagen and hyaluronic acid production. Morus Alba further enhances antioxidant defense by scavenging free radicals and inhibiting ROS generation, while its anti-inflammatory action modulates proteins like TNF, IL-6, and IRS1 and inhibits leukocyte migration, contributing to overall skin calming and evening tone.