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Moumoujus

LEONURUS SIBIRICUS CALLUS CULTURE EXTRACT.

Insufficient Data / SKIN CONDITIONING

Leonurus Sibiricus Callus Culture Extract is a plant-derived ingredient, cultivated from the motherwort plant, known for its traditional medicinal uses. It is currently being investigated for its potential to offer protective and regenerative benefits to the skin, primarily through antioxidant and anti-inflammatory pathways.

Summary

Antioxidant Anti-inflammatory Skin Conditioning DNA Repair Support Antibacterial

Science

Mechanism of Action

Research indicates that Leonurus Sibiricus extracts, including its callus culture form, operate by reducing intracellular reactive oxygen species (ROS), thereby exhibiting antioxidant activity. It enhances the expression of key antioxidant enzymes such as SOD2, CAT, and GPx. Furthermore, this extract demonstrates anti-inflammatory properties, stimulates cellular DNA repair, and possesses antibacterial capabilities, contributing to overall skin health and resilience.

Research

Clinical Evidence

Low confidence
Effective range 0.05–0.5%
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

No data within the research suggests that Leonurus Sibiricus Callus Culture Extract is commonly 'dusted' or used at concentrations below a threshold of efficacy for its reported benefits.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

The optimal pH range for the stability of Leonurus Sibiricus Callus Culture Extract itself is not specifically documented. A study on the leonurine content of a Leonurus sibiricus ethanolic extract noted robustness in a pH buffer solution between 7.8 and 8.0 for analytical quantification, but this does not directly indicate optimal stability for cosmetic formulation.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Specific safety assessments by recognized regulatory bodies such as the CIR Expert Panel, SCCS, or FDA for LEONURUS SIBIRICUS CALLUS CULTURE EXTRACT are not readily available. For the broader 'Leonurus Sibiricus Extract,' EWG Skin Deep indicates low concerns regarding cancer, allergies & immunotoxicity, and developmental & reproductive toxicity, with limited to fair data availability. Its irritancy and comedogenicity are currently unknown as per INCI Decoder.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

While Leonurus Sibiricus Callus Culture Extract demonstrates promising in vitro antioxidant, anti-inflammatory, and DNA repair properties based on studies of general Leonurus sibiricus extracts, the lack of specific clinical efficacy data on human skin for the callus culture extract form necessitates further investigation to fully ascertain its dermatological benefits and optimal application.

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