Science
Mechanism of Action
Leontopodium Alpinum Flower Extract operates through multiple pathways to enhance skin health. It exhibits potent antioxidant capabilities, effectively neutralizing reactive oxygen species and free radicals to mitigate oxidative stress. The extract also provides anti-inflammatory action, reducing skin irritation and redness by influencing key inflammatory markers. Furthermore, it supports the skin's natural regeneration processes, helps maintain elasticity by inhibiting enzymes such as hyaluronidase and MMP-2 which are involved in collagen degradation, and strengthens the skin's crucial moisture barrier to prevent dehydration. Emerging research also points to its capacity to protect against environmental damage, including blue light.
Research
Clinical Evidence
Medium confidence3-5%
Key findings
- 01 Topical application of Leontopodium Alpinum Flower Extract at 3-5% is recommended for enhancing antioxidant protection and supporting skin hydration.
- 02 Studies involving Leontopodium Alpinum Callus Culture Extract at concentrations from 0.1% to 1% demonstrated increased cellular vitality and significant radical-scavenging activity, outperforming 0.001% Vitamin C.
- 03 Specific components of the Callus Culture Extract (e.g., leontopodic acid A), at 5-20 μM in vitro, exhibited protective effects against blue light-induced damage, improved cell viability, boosted COI-1 expression, and inhibited MMP-1.
- 04 Consistent in-vivo application of Leontopodium Alpinum Callus Culture Extract has been shown to improve periorbital wrinkles, enhance skin elasticity, and increase dermal density and thickness.
- 05 In-vivo trials with a proprietary Callus Culture Extract (Majestem) reported visible lifting action, including skin tightening on the neck by up to 56% in three weeks and smoothing of crow's feet wrinkles by up to 75% after six weeks.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
For optimal preservation, store the extract refrigerated upon arrival and maintain temperatures below 25°C (77°F). Avoid exposure to extreme heat, cold, or freezing. Protection from light, such as through the use of blue glass bottles, is recommended to prevent loss of effectiveness.
Safety
Safety Profile
Generally regarded as safe for topical application, possessing a high safety profile. Derived naturally from plants, it typically does not induce allergic reactions. However, individuals with specific plant sensitivities or highly sensitive skin types are advised to perform a patch test prior to widespread use.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Leontopodium Alpinum Flower Extract is a valuable ingredient offering significant antioxidant, anti-inflammatory, and hydrating benefits, with strong support for its anti-aging and protective effects against environmental stressors.
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