Science
Mechanism of Action
LEDEBOURIELLA SESELOIDES/LOTUS CORNICULATUS SEED EXTRACT targets key pathways to improve skin condition. It primarily inhibits lipogenesis in SZ95 sebocytes and oily human skin, reducing lipid synthesis via both linoleic acid (LA) and dihydrotestosterone (DHT) pathways to effectively manage sebum secretion. Rich in natural flavonoids and bioactive compounds such as kaempferol, quercetin, isorhamnetin, oleamide, and linoleamide, it exerts significant antioxidant activity, neutralizing free radicals, and possesses anti-inflammatory properties. Furthermore, these compounds work to fortify the epidermal barrier, enhancing moisture retention and maintaining skin elasticity for a more youthful appearance.
Research
Clinical Evidence
Medium confidence5%
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
A Canadian screening assessment indicates that while Lotus corniculatus extract may contain cyanogenic glycosides or hydrogen cyanide (HCN), the risk of harm from cosmetic exposure is considered low due to limited consumer contact and HCN's volatility. In a clinical study using 5% topical application over 4 weeks, no adverse reactions were reported, further supporting its low risk profile in cosmetic formulations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This extract is a valuable multi-functional ingredient, clinically effective in reducing sebum, providing significant antioxidant protection, and enhancing skin barrier function, with a favorable safety profile for all skin types including sensitive.
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References
Sources