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Moumoujus

LAVANDULA ANGUSTIFOLIA CALLUS EXTRACT.

Insufficient Data / ANTIMICROBIAL, HAIR CONDITIONING, SKIN CONDITIONING, SKIN PROTECTING

Lavandula Angustifolia Callus Extract (LCE) is a plant-derived ingredient engineered to enhance cellular vitality and provide significant antioxidant protection. It actively reduces oxidative stress and melanin content, while also supporting wound healing processes. Furthermore, LCE acts as a protective shield against various environmental aggressors and microorganisms.

Summary

flavouring fragrance perfuming skin protecting antimicrobial agent hair conditioning agent skin conditioning agent

Science

Mechanism of Action

LCE functions by strategically modulating the Nrf2 pathway, a critical cellular defense system. It upregulates Nrf2 and associated antioxidant response element (ARE) genes, concurrently downregulating Kelch-like ECH-associated protein 1 (Keap1). This precise modulation increases the expression of key antioxidant enzymes, leading to a reduction in free radicals, inhibition of lipid peroxidation, and elevated glutathione (GSH) levels, thereby fortifying the skin's defense against oxidative damage. Beyond its antioxidant capabilities, LCE improves wound healing, exhibits antimicrobial properties, and creates a protective barrier on the skin's surface against harmful substances, irritants, and pathogens.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Unknown
Optimal pH N/A
0 7 14

Stability

The stability of LCE in a finished product is sensitive to factors such as pH, exposure to light, and oxygen. Optimal performance in-formula is dependent on the commercial grade, the chosen vehicle (e.g., aqueous, glycolic, hydroalcoholic), and adherence to quality specifications regarding impurities, residues, and microbiological integrity.

Conflicts

  • Compatibility challenges with the preservative system are noted, as this ingredient does not provide comprehensive finished-product preservation.
  • Potential for turbidity or precipitation issues when combined with certain preservatives.
  • Requires careful management of its inherent color and odor, particularly in formulations designed to be pale or subtly fragranced.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel considered 'Lavandula Angustifolia (Lavender) Callus Extract' for review in 2016, indicating a pending safety assessment. A definitive maximum safe concentration has not been established. Due to the complex nature and potential compositional variability of plant extracts, a comprehensive safety assessment is recommended for the finished product, considering individual user tolerability.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Insufficient Data

LAVANDULA ANGUSTIFOLIA CALLUS EXTRACT demonstrates promising mechanisms for antioxidant defense and skin protection, yet robust clinical efficacy data, including effective concentrations and comprehensive safety reviews, are currently limited.

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