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LAURYL ISOPENTYL-PEG/PPG-18/18 METHICONE.

Valuable CAS 1112315-26-0 / SURFACTANT - EMULSIFYING

LAURYL ISOPENTYL-PEG/PPG-18/18 METHICONE is a multifaceted silicone copolymer primarily functioning as an emulsifier and emulsion stabilizer, enabling the uniform blending of oil and water phases in formulations. It contributes to a desirable skin feel and offers additional benefits as a solvent, with reported antimicrobial and moisturizing properties.

Summary

Surfactant Emulsifying Emulsion Stabilizing Solvent Antimicrobial Moisturizer/Humectant

Science

Mechanism of Action

This ingredient operates as a surfactant by reducing interfacial tension between incompatible substances through its unique molecular structure, which possesses both lipophilic and hydrophilic segments. It effectively facilitates and stabilizes emulsions, particularly water-in-silicone systems. As a derivative of polyethylene glycol, it is inherently water-soluble and non-greasy, which often correlates with good skin tolerance. Manufacturers also indicate its activity as a broad-spectrum antimicrobial and a moisturizer.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

This silicone emulsifier is integral for creating stable water-in-silicone emulsions, often demonstrating robust stability when subjected to protocols such as storage at 110°F for 4 weeks without compromise in pH, viscosity, color, odor, texture, or visual separation. It possesses an indicated HLB value of approximately 2.2, characterizing it as a water-in-oil emulsifier.

Conflicts

  • Stabilizing salts (e.g., NaCl or MgSO4) should be omitted from water-in-silicone emulsions formulated with similar silicone emulsifiers, as they can lead to destabilization of the composition.

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has deemed this ingredient safe for use, including it in a safety assessment of related polyoxyalkylene siloxane copolymers. Genotoxicity testing of a closely related lauryl PEG/PPG-18/18 methicone indicated no genotoxic activity at concentrations up to 1500 μg/plate. Clinical studies on related dimethicone copolyol ingredients reported them to be non-irritating and non-sensitizing, even when applied at 40% in aqueous solution or undiluted. Dimethicone-based compounds are generally not associated with comedogenicity. The ingredient has been voluntarily reported to the FDA's VCRP for use in 53 leave-on and 32 rinse-off cosmetic products.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

LAURYL ISOPENTYL-PEG/PPG-18/18 METHICONE is a valuable and safe ingredient, adept at stabilizing challenging water-in-silicone emulsions while offering versatile functions as a solvent, and contributing a pleasant skin feel with potential moisturizing and antimicrobial benefits across all skin types.

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