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LAUROYL PG-TRIMONIUM CHLORIDE.

Optional CAS 53171-04-3 / ANTISTATIC, HAIR CONDITIONING

Lauroyl PG-Trimonium Chloride is a versatile quaternary ammonium compound predominantly utilized for its hair conditioning and antistatic properties. It also functions as an emulsifier and preservative, contributing to product stability and a smooth skin feel at precisely controlled concentrations.

Summary

Antistatic Hair Conditioning Emulsifying Preservative Moisturizing

Science

Mechanism of Action

As a quaternary ammonium compound, Lauroyl PG-Trimonium Chloride operates by neutralizing electrical charges, effectively reducing frizz and enhancing hair manageability. In cosmetic formulations, it acts as an emulsifier, facilitating the homogenous blending of oil and water, and functions as a preservative to inhibit microbial growth. For skin, it aids in moisture retention within products and contributes to a desirable texture and feel.

Research

Clinical Evidence

Medium confidence
Effective range 0.1–3%
Optimal

1%

Key findings

  1. 01 Effective as a conditioning agent in hair care (shampoo, conditioner, treatments) providing softness, with 1% recommended as an optimal dosage.
  2. 02 Related 'trimonium' compounds are considered safe for use in leave-on products up to 0.25% when formulated to be non-irritating.
  3. 03 EU regulations permit up to 0.1% concentration for related Laurtrimonium Chloride when used as a preservative in finished cosmetic products.

Transparency

Dusting Analysis

Commonly dusted
Min. effective
0.25%
Red flag below
0.25%

While deemed safe in concentrations up to 0.25% for similar compounds in leave-on products, and up to 0.1% when functioning as a preservative, this ingredient is flagged as a potential irritant and allergen. Exceeding these thresholds, especially in leave-on skin formulations, increases the risk of sensitization or irritation without rigorous non-irritancy testing.

The Formula

Formulation

Solubility
Water
Optimal pH 3.5 – 7
0 7 14

Stability

Stable within a pH range of 3.5 to 7.0. The ingredient is heat tolerant, but temperatures exceeding 80°C should be avoided during processing.

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
0.25%
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) Expert Panel concluded that a group of similar quaternary ammonium salts, including Lauroyl PG-Trimonium Chloride, are safe at current use concentrations when formulated to be non-irritating. For general leave-on products, this concentration can be up to 0.25%. However, EU regulation limits the related Laurtrimonium Chloride to 0.1% when specifically used as a preservative. It is considered a potential irritant and allergen, with EWG noting low to moderate concerns for allergies, immunotoxicity, and irritation, and EPA suggesting moderate human health risk.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Optional

While primarily a hair conditioning agent, Lauroyl PG-Trimonium Chloride offers optional benefits in skincare as an emulsifier, preservative, and texture enhancer, provided it is formulated precisely within recommended low concentrations to mitigate its potential for irritation.

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