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LAURALKONIUM CHLORIDE.

Insufficient Data CAS 139-07-1 / ANTISTATIC, PRESERVATIVE

Lauralkonium Chloride is a cationic surfactant belonging to the quaternary ammonium compound family, primarily utilized for its antimicrobial properties. It functions as a preservative in various cosmetic and ophthalmic formulations, disrupting microbial membranes.

Antimicrobial Preservative Antistatic agent

Science

This compound exerts its action through a cationic head and a hydrophobic tail, which enables interaction with negatively charged microbial cell membranes. This interaction leads to membrane disruption, effectively functioning as a disinfectant and preservative by controlling microbial growth.


Research

Low confidence
Effective range N/A
Optimal

0.005%


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

No specific optimal pH range for stability was identified. Lauralkonium Chloride is compatible with acidic ophthalmologically acceptable drug formulations. While an estimated water solubility of 22.47 mg/L at 25 °C is reported, there is also a contradictory statement of insolubility in water, suggesting potential formulation challenges depending on desired concentration. It exhibits solubility in DMSO.


Safety

CIR Status
Insufficient data
Sensitization risk Moderate

The CIR Expert Panel categorized 'Alkonium Chlorides and Bromides', including Lauralkonium Chloride, as having 'insufficient data' following a re-review in March 2023. A related compound, Benzalkonium Chloride, was previously deemed 'safe as used at concentrations up to 0.1% free active ingredient'. The FDA recognizes Lauralkonium Chloride for specific applications as a food additive/microorganism control (21 CFR 172.165, 173.320). EWG assigns a 'MODERATE' concern for 'Asthma / Respiratory' and 'Skin Allergies & Irritation', alongside 'LOW' concerns for 'Developmental and Reproductive Toxicity', 'Use Restrictions', and 'Cancer'.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Moderate
Comedogenicity Unknown

Our Assessment

Insufficient Data

Due to 'insufficient data' from the CIR Expert Panel regarding its general cosmetic safety, further research is required to establish its comprehensive utility and optimal usage in broader skincare applications, despite its recognized antimicrobial efficacy in specific contexts.


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