Science
Mechanism of Action
This extract operates through multiple pathways to benefit the skin. Its phenolic and flavonoid constituents provide antioxidant activity by scavenging DPPH radicals and inhibiting lipid peroxidation. Specific compounds, 17(20)E-dyscusin B and 17(20)Z-dyscusin B, demonstrate potent nitric oxide (NO) inhibition, suggesting a key anti-inflammatory mechanism. Furthermore, the extract, similar to other parts of the plant, may inhibit tyrosinase activity due to its phenolic and flavonoid profile, contributing to a potential skin lightening effect.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Polyphenols within the extract can have enhanced stability and antioxidant activity when incorporated using encapsulation techniques such as spray-drying or freeze-drying.
Safety
Safety Profile
Safety assessments for a general Lansium domesticum extract (not explicitly leaf) indicated no irritation or allergic reactions at 1% and 3% concentrations in a Single Closed Patch Test (SCPT). A 2% concentration of Lansium domesticum fruit extract also proved safe for skin and eyes. However, a 5% concentration of the general extract caused irritation in 1.9% of subjects in an SCPT, suggesting a concentration-dependent risk. Specific safety assessments from regulatory bodies like CIR, SCCS, or FDA for Lansium Domesticum Leaf Extract are not available.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Lansium Domesticum Leaf Extract offers promising antioxidant, anti-inflammatory, and potential skin lightening benefits through well-defined mechanisms, though clinical efficacy data for the leaf extract itself is currently limited.
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References
Sources