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Moumoujus

LAMIUM ALBUM LEAF EXTRACT.

Valuable CAS 84012-23-7 / SKIN CONDITIONING

Lamium Album Leaf Extract, derived from White Dead Nettle, is a multi-functional botanical ingredient prized for its skin conditioning, astringent, and reparative properties. It actively hydrates the skin, refines pores, and offers robust antioxidant and anti-inflammatory benefits to promote overall skin health.

Summary

skin conditioning astringent antioxidant anti-inflammatory wound healing

Science

Mechanism of Action

This extract functions as a versatile skin conditioning agent, enhancing hydration levels. Its astringent qualities help to firm and tone the skin by temporarily constricting pores and forming a protective surface layer. Rich in tannins, phenolic acids (such as rosmarinic and chlorogenic acid), flavonoids, saponins, and iridoids, it delivers significant antioxidant protection against free radical damage and oxidative stress. Furthermore, it possesses anti-inflammatory, haemostatic, and antimicrobial attributes. It promotes skin repair by stimulating fibroblast maturation, collagen synthesis, and new blood vessel formation, while also exhibiting cytoprotective effects on human fibroblasts and assisting in the regulation of sebaceous secretions.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 An ointment containing 5% Lamium album methanol extract significantly increased fibroblast maturation, collagen deposition, and neovascularization, leading to improved wound healing rates in rat models compared to control.
  2. 02 Reduced the production of reactive oxygen species (ROS) in HepG2 cells in vitro, indicating notable antioxidant and cytoprotective properties.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While the extract is generally well-tolerated, in vitro studies indicated considerable cytotoxicity for ethyl acetate and methanol extracts at concentrations exceeding 125 µg/mL on human skin fibroblasts (HSFs). However, heptane extracts demonstrated high viability (over 60%) even at high concentrations, suggesting solvent-dependent safety profiles. Rigorous safety assessments are required for cosmetic ingredients in the EU.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Lamium Album Leaf Extract is a valuable botanical offering extensive benefits, including hydration, astringency, antioxidant protection, anti-inflammatory effects, and wound healing support, suitable for all skin types with low irritation risk.

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