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Moumoujus

LAMIUM ALBUM FLOWER/LEAF/STEM EXTRACT.

Valuable CAS 84012-23-7 / SKIN CONDITIONING

Lamium Album Flower/Leaf/Stem Extract, derived from the white dead nettle, is a multifaceted botanical ingredient recognized for its soothing and restorative properties. It provides comprehensive support for skin health, making it particularly beneficial for sensitive and compromised complexions.

Summary

Anti-inflammatory Antioxidant Astringent Skin Conditioning Antimicrobial Wound Healing Sebum Regulation

Science

Mechanism of Action

This botanical extract supports skin health through diverse mechanisms. It acts as an anti-inflammatory agent by inhibiting pro-inflammatory cytokines such as IL-8 and TNF-α, and by modulating arachidonic acid metabolism via the lipoxygenase pathway. Its rich content of phenolic acids, polyphenols, and flavonoids provides significant antioxidant protection against free radical damage. The extract also functions as an astringent, helping to refine pores and firm the skin, while its mucilage content contributes to skin conditioning and protective film formation. Additionally, it offers antimicrobial effects (antiseptic, antibiotic, bacteriostatic) and supports wound healing, partly attributed to its triterpenes, and assists in sebum regulation and microbial balance on the scalp.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 An ointment containing 5% methanol extract of Lamium album aerial parts significantly enhanced wound healing in rats by promoting fibroblast maturation, collagen deposition, and neovascularization.
  2. 02 Ethanol extracts from flowers and aerial parts significantly inhibited the production of reactive oxygen species (ROS) and the secretion of myeloperoxidase and interleukin-8 (IL-8) in human neutrophils. The flower extract at 100 μg/mL further inhibited TNF-α cytokine secretion.
  3. 03 An aqueous extract demonstrated in vitro inhibition of lipoxygenase activity at an approximate concentration of 1.5 mg/mL.

Transparency

Dusting Analysis

Not commonly dusted

With well-documented anti-inflammatory, antioxidant, and wound-healing properties demonstrated across various experimental models, this ingredient exhibits clear efficacy and is not considered a 'dusting' ingredient.

The Formula

Formulation

Solubility
Water
Optimal pH 3.9 – 7.2
0 7 14

Stability

The aqueous extract maintains stability within a pH range of 3.9 to 7.2. It is free from essential oils and declarable fragrance allergens, offering broad compatibility with common cosmetic solvents and oils, including pentylene glycol, propylene glycol, glycerin, jojoba oil, squalane, and sunflower oil.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Although formal safety assessments by CIR, SCCS, or FDA are not available, Lamium Album Extract is generally considered mild and non-irritating. It is suitable for sensitive skin due to its lack of stinging hairs, unlike related plants.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Lamium Album Flower/Leaf/Stem Extract is a valuable botanical, providing significant anti-inflammatory, antioxidant, and wound-healing benefits, making it an excellent choice for soothing and restoring sensitive and compromised skin.

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