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Moumoujus

LAMIUM ALBUM EXTRACT.

Valuable CAS 84012-23-7 / ASTRINGENT, FRAGRANCE

Lamium Album Extract is a versatile botanical ingredient renowned for its multifaceted benefits, including potent antioxidant and anti-inflammatory properties, alongside its ability to condition the skin. It helps to hydrate, soothe, and regulate skin's natural balance, making it suitable for a broad range of skin types and concerns.

Summary

Astringent Skin Conditioning Antioxidant Anti-inflammatory Antibacterial Wound Healing Moisturizing Sebum Regulating

Science

Mechanism of Action

This extract functions as a comprehensive skin conditioning agent, enhancing hydration and overall skin health. Its astringent qualities temporarily refine pores, contributing to a firmer, more toned appearance. Rich in active compounds such as flavonoids, phenolic acids, iridoids, and tannins, it offers significant antioxidant protection by neutralizing free radicals and impeding oxidative damage. Additionally, its phenolic compounds and iridoids provide anti-inflammatory effects by inhibiting lipoxygenase activity. The extract also exhibits broad-spectrum antibacterial efficacy, particularly against Gram-positive bacteria, and its mucilage content forms a protective, soothing, and moisturizing film on the skin. It supports wound healing processes and helps balance sebaceous secretions.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro studies demonstrated that Lamium Album Extract at 50 µg/mL significantly reduced reactive oxygen species (ROS) production in HepG2 cells, indicating strong antioxidant and cytoprotective capabilities.
  2. 02 Another in vitro study on Human Skin Fibroblast (HSF) cells showed that while ethyl acetate and methanol extracts exhibited considerable cytotoxicity above 125 µg/mL, heptane extracts maintained high cell viability (>60%) even at elevated concentrations.

Transparency

Dusting Analysis

Not commonly dusted

There is no research data to suggest that Lamium Album Extract is commonly 'dusted' or used at ineffective concentrations in formulations. The available clinical data points to specific effective concentrations for demonstrated benefits.

The Formula

Formulation

Solubility
Both
Optimal pH 3.9 – 7.2
0 7 14

Stability

The extract demonstrates optimal chemical-physical stability within a pH range of 3.9 to 7.2. The choice of extraction method significantly influences the extract's composition, biological activity, and stability; for instance, aqueous extracts are noted to be free from essential oils and declarable fragrance allergens.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While formal CIR, SCCS, or FDA safety assessments are not available, Lamium Album Extract is generally regarded as mild and non-irritating for cosmetic use. In vitro studies observed considerable cytotoxicity at concentrations exceeding 125 µg/mL for ethyl acetate and methanol extracts on HSF cells; however, heptane extracts demonstrated high viability. The absence of stinging hairs in the plant also contributes to its perceived mildness.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Lamium Album Extract is a valuable botanical ingredient offering broad benefits including antioxidant, anti-inflammatory, and sebum-regulating properties, with low irritancy and wide skin compatibility, making it suitable for diverse precision skincare formulations.

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