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LACTUCA SCARIOLA SATIVA LEAF EXTRACT.

Valuable CAS 84776-66-9 / 90046-10-9 / SKIN CONDITIONING

Lactuca Scariola Sativa Leaf Extract, derived from wild lettuce, is a multi-functional botanical ingredient celebrated for its potent antioxidant and antimicrobial properties. Rich in vital vitamins and minerals, it actively supports skin regeneration, anti-aging, and soothing, promoting overall skin vitality and a healthier appearance.

Anti-acne Skin regeneration Anti-aging Soothing Antioxidant Nourishing Toning Softening Smoothing Skin conditioning

Science

This extract operates through a synergistic blend of vitamins (A, B1, C, E) and essential minerals (iron, calcium, potassium, lysine, tyrosine). Vitamin A facilitates increased cell turnover, contributing to skin revitalization. Its significant antioxidant capacity arises from the radical scavenging effects of key active compounds, including quercetin-3-O-beta-D-glucopyranoside, luteolin-7-O-beta-D-glucopyranoside, luteolin, quercetin, and kaempferol. Additionally, it enhances skin microcirculation, which contributes to its nourishing, toning, softening, and smoothing benefits.


Research

High confidence
Effective range 12.5 mg/mL–200 mg/mL%
Optimal

N/A

Key findings

  1. 01 Demonstrated 9.35% antioxidant activity (inhibition %).
  2. 02 Showed 16.43% antioxidant activity (inhibition %).
  3. 03 Yielded 29.17% antioxidant activity (inhibition %).
  4. 04 Achieved 53.82% antioxidant activity (inhibition %), and antimicrobial activity with inhibition zones of 20mm for Staphylococcus aureus, 13mm for Bacillus cereus, 17mm for Escherichia coli, and 14mm for Pseudomonas aeruginosa.
  5. 05 Exhibited 76.53% antioxidant activity (inhibition %), and enhanced antimicrobial activity with inhibition zones of 22mm for Staphylococcus aureus, 14mm for Bacillus cereus, 19mm for Escherichia coli, and 16mm for Pseudomonas aeruginosa.

Transparency

Not commonly dusted

Data on 'dusting' or common over-formulation practices for Lactuca Scariola Sativa Leaf Extract are not available within the provided research.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

The optimal pH range for this extract's stability in cosmetic formulations has not been specifically identified. Water-soluble components within the extract have been noted to inhibit DNA damage.


Safety

CIR Status
Not reviewed
Sensitization risk Low

Lactuca Scariola Sativa Leaf Extract has not undergone formal review by the Cosmetic Ingredient Review (CIR) or the Scientific Committee on Consumer Safety (SCCS). It is not listed by the FDA as a cosmetic color additive. EWG Skin Deep assesses this ingredient with a 'LOW' concern rating for potential cancer, allergies & immunotoxicity, developmental and reproductive toxicity, and use restrictions. However, for inclusion in EWG VERIFIED products, adequate substantiation is required.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

This versatile botanical extract offers a compelling profile of benefits, including robust antioxidant and antimicrobial activity, coupled with skin regenerating and soothing properties, making it a valuable asset for a diverse range of precision skincare formulations targeting multiple skin concerns.


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