Science
Mechanism of Action
This extract operates by supporting the life cycle and health of new epidermal cells, crucial for the skin's protective barrier. It stimulates the production of vital antimicrobial peptides, which contribute to a healthy skin flora and facilitate cell communication. By encouraging a thicker stratum corneum and supporting keratinocytes and barrier proteins like filaggrin, it significantly reduces trans-epidermal water loss (TEWL), resulting in visibly more supple skin. Furthermore, it modulates inflammatory markers, potentially leading to calmer, less reactive skin. Though not a live probiotic, it delivers similar benefits by supporting a balanced skin microbiome. Its influence extends to epidermal growth, activating gene expression for proteins essential in binding live skin cells (e.g., Occludin, Desmocollin 1, Desmoglein 1), and enzymes (Kallikrein 5 and 7) responsible for the controlled shedding of dead skin cells.
Research
Clinical Evidence
Medium confidence3%
Key findings
- 01 Applied twice daily for 4 days, demonstrated a quantifiable increase in stratum corneum thickness (approximately 2 µm) and a reduction in trans-epidermal water loss, indicative of enhanced barrier recovery and skin renewal.
- 02 Investigated for its anti-inflammatory potential in the management of acne vulgaris, suggesting broader therapeutic utility.
Transparency
Dusting Analysis
Given its demonstrated efficacy at concentrations as low as 3% and a maximum reported usage of 5.6% for similar ferments, Lactococcus Ferment Extract is utilized as a functional active ingredient, not typically 'dusted' at negligible percentages.
The Formula
Formulation
Stability
For optimal stability, it is recommended to incorporate the ingredient during the cooling phase of formulation, at temperatures below 70°C (158°F), and prior to the addition of thickening agents such as xanthan gum or Carbopol Ultrez 10.
Safety
Safety Profile
The CIR Expert Panel has deemed similar ferment ingredients, including Lactobacillus Ferment and its derivatives, safe for use in cosmetics, with reported concentrations up to 5.6% in leave-on skin products. Cosmetic formulators are advised to consider potential skin depigmentation effects if observed with similar ingredients, as this would classify as a drug effect. No specific FDA drug status or restrictions were identified for Lactococcus Ferment Extract.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Lactococcus Ferment Extract is a valuable postbiotic ingredient, proven to enhance skin barrier function and promote cellular renewal, making it suitable for a wide range of skin types seeking improved resilience and a balanced microbiome.
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