Science
Mechanism of Action
The combined ferment filtrate delivers comprehensive skin benefits. Lactobacillus ferment filtrate actively supports a balanced skin microbiome and optimal pH, while functioning as a potent antioxidant to neutralize free radicals and mitigate premature aging. It strengthens the skin barrier, enhances moisture retention, stimulates beneficial bacteria growth, and promotes cell renewal, contributing to improved skin regeneration and natural radiance. Its anti-inflammatory, anti-bacterial, and conditioning properties may also assist in managing conditions like acne and rosacea, alongside boosting collagen synthesis and ATP production. Schizosaccharomyces ferment filtrate, a yeast-derived component, provides vital nutrients and additional antioxidant protection. It is observed to reduce inflammation, stimulate collagen production for enhanced elasticity, and refine skin texture, diminishing the appearance of fine lines and wrinkles. Together, these ferments fortify the skin's resilience against environmental stressors, brighten the complexion, and may inhibit tyrosinase activity to modulate melanin synthesis.
Research
Clinical Evidence
Medium confidence1-20%
Key findings
- 01 In an in-vivo study involving 5 participants, a related Lactobacillus Ferment Lysate Filtrate demonstrated a 47% reduction in skin redness, indicating significant soothing and anti-irritant potential.
- 02 Lactobacillus ferment showed results in reducing skin sensitivity.
- 03 Lactobacillus ferment demonstrated both anti-microbial and anti-inflammatory properties.
- 04 Lactobacillus extracts have been shown to stimulate beta-defensin production in skin cells, generally in a dose-dependent manner.
Transparency
Dusting Analysis
Effective concentrations for key benefits, such as soothing (5%) and sensitivity reduction (1%), fall within a reasonable and commonly used range. This indicates the ingredient is typically incorporated at levels where its effects are clinically relevant, rather than merely for label appeal.
The Formula
Formulation
Stability
Optimal stability is achieved within a pH range of 4.0-5.0. For best integration, incorporate directly into aqueous formulations at temperatures below 50°C.
Safety
Safety Profile
The CIR Expert Panel concluded that Lactobacillus Ferment and its filtrates are safe for cosmetic use. However, for Schizosaccharomyces Ferment Filtrate, the CIR Panel found data insufficient for a full safety determination. A critical restriction from CIR advises formulators to use these ingredients in a manner that avoids skin depigmentation, due to their potential to inhibit tyrosinase activity. While no specific SCCS or FDA approval status for the combined ingredient was found, its individual components are present in FDA VCRP and RLD data for cosmetic product use.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This ferment filtrate offers a robust portfolio of benefits, including significant soothing, barrier support, and anti-aging properties, making it a valuable addition for diverse skin concerns despite safety considerations regarding tyrosinase inhibition.
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References
Sources