Science
Mechanism of Action
The ingredient operates through a multi-faceted approach, leveraging the distinct benefits of its fermented components. Lactobacillus ferment filtrate actively fortifies the skin's natural barrier, minimizes irritation, and fosters a balanced skin microbiome. It delivers essential amino acids, peptides, organic acids (such as lactic acid), enzymes, and antioxidants, exhibiting both antimicrobial and anti-inflammatory actions. Notably, it may contribute to DNA repair and defense against environmental aggressors. Saccharomyces ferment filtrate contributes to overall skin vitality by supplying vital nutrients and antioxidants, reducing inflammatory responses, stimulating collagen production, and improving skin elasticity and texture. This results in a visible reduction of fine lines and wrinkles. Fermented turmeric, specifically when processed with Lactobacillus fermentum, demonstrates enhanced curcumin bioavailability and potent anti-inflammatory effects through the suppression of c-Jun N-terminal kinase (JNK), tumor necrosis factor-alpha (TNF-α), and Toll-like receptor-4 (TLR4) pathways. Its fermentation also boosts antioxidant capacity and improves curcumin's solubility, making its benefits more accessible to the skin.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Lactobacillus Ferment demonstrated a reduction in skin sensitivity.
- 02 Lactobacillus Ferment proved effective as an anti-acne treatment.
- 03 An in-vivo study with 5 participants observed a 47% reduction in redness with Lactobacillus Ferment Lysate Filtrate.
- 04 Continuous application of Saccharomyces boulardii fermented product filtrate for four weeks led to an average reduction in trans-epidermal water loss (TEWL) by 37.2% and an increase in stratum corneum hydration by 62.5%.
- 05 L. fermentum-fermented turmeric exhibited anti-inflammatory activity by significantly reducing nitrite levels and suppressing TNF-α and TLR4 expression in LPS-induced RAW 264.7 cells, alongside promoting cell survival and scavenging DPPH radicals.
Transparency
Dusting Analysis
This ingredient offers multiple scientifically supported benefits for skin health, making it a valuable active rather than a 'dusting' ingredient.
The Formula
Formulation
Stability
This water-soluble ingredient should be incorporated into water-based formulations or the water phase of emulsions. For optimal stability, it is recommended to add it during the cooling phase, specifically when temperatures are below 70°C (158°F), and prior to the inclusion of thickening agents such as xanthan gum or Carbopol Ultrez 10. The fermented turmeric component has an optimal pH range of 6.5-7.0 post-fermentation. It may necessitate co-preservatives to establish a comprehensive preservation system.
Synergies
- Other hydrators (e.g., hyaluronic acid)
- Antioxidants (e.g., Vitamin C, E)
- Barrier-supporting ceramides
Safety
Safety Profile
The CIR Expert Panel has concluded that Lactobacillus Ferment and its derivatives (Filtrate, Lysate) are safe for cosmetic use, with Lactobacillus Ferment applied at concentrations up to 5.6% in face and neck products. The Good Scents Company classifies the combined LACTOBACILLUS/SACCHAROMYCES/TURMERIC FERMENT EXTRACT FILTRATE as an antioxidant with no identified hazards based on GHS. No specific SCCS or FDA status for the precise combination was found, but its individual components are generally regarded as safe.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This multi-fermented extract offers significant benefits across hydration, barrier support, anti-inflammatory action, and antioxidant protection, making it a highly valuable active for diverse skin concerns.
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