Science
Mechanism of Action
This sophisticated ingredient operates through a multi-pronged mechanism, combining the distinct actions of its fermented components and botanical extract. Lactobacillus ferment functions as a DNA repair enzyme, shielding the skin from environmental stressors, while also exhibiting antimicrobial and anti-inflammatory properties, making it beneficial for concerns such as acne and rosacea. It further contributes to maintaining a healthy skin microbiome and may offer skin-lightening effects by inhibiting tyrosinase. The Saccharomyces/Rehmannia glutinosa root ferment extract amplifies these benefits, providing robust antioxidant, emollient, and protective functions. The fermentation process is known to enhance the bioavailability and efficacy of the Rehmannia glutinosa root extract, which independently offers antioxidant properties, moisturizing and soothing effects, reduction of inflammation, promotion of skin regeneration, collagen production, and strengthening of the skin's protective barrier, leading to improvements in skin tone and texture.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Clinical investigations into Lactobacillus ferment demonstrated notable results in reducing skin sensitivity.
- 02 Lactobacillus ferment at 5% concentration proved effective for anti-acne benefits, reducing the size and redness of acne lesions more rapidly than salicylic acid.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
This ingredient typically presents as a clear to slightly turbid aqueous liquid. The Lactobacillus ferment component can additionally function as a natural preservative within cosmetic formulations. The complete fermented blend is highly adaptable and can be seamlessly integrated into various aqueous cosmetic systems, including gels, solutions, serums, and emulsions.
Synergies
- Fermentation enhances the efficacy, bioavailability, and antioxidant capacity of the botanical extract.
- The combination of multiple ferments and a root extract provides broader spectrum benefits than individual components.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that Lactobacillus Ferment, along with other related ferment ingredients, is safe for use in cosmetics at current concentrations and practices. A critical note was issued regarding its potential skin-lightening effect, which is classified as a drug effect, advising formulators to prevent unintended skin depigmentation. For Saccharomyces-derived ingredients, CIR supports safety for those from species with established dermal sensitization and food use status. The unfermented Rehmannia glutinosa root extract is generally considered low risk. While individual components demonstrate favorable safety profiles and low irritancy, a specific CIR, SCCS, or FDA assessment for the exact combined ingredient 'LACTOBACILLUS/SACCHAROMYCES/REHMANNIA GLUTINOSA ROOT FERMENT EXTRACT' is not directly available, with 'Saccharomyces/Rehmannia Glutinosa Root Ferment Extract' noted as 'Not rated' by Paula's Choice.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This highly versatile fermented extract provides significant antioxidant, anti-inflammatory, and skin-protecting benefits, fostering a balanced skin microbiome and effectively addressing concerns such as sensitivity and acne, establishing it as a valuable ingredient in diverse skincare formulations.
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