Science
Mechanism of Action
The ingredient functions through the synergistic actions of its diverse components. Lactobacillus Ferment Lysate Filtrate provides beneficial postbiotics, including metabolites, enzymes, and peptides, which are reported to promote oxygen uptake, collagen production, and ATP synthesis in vitro, translating to soothing and anti-irritant effects in vivo. Leuconostoc Ferment Filtrate contributes antimicrobial activity and acts as a moisturizing and conditioning agent, partly due to its natural salicylic acid content (18-22%). The inclusion of fermented Artemisia Annua extract boosts the ingredient's antioxidant capacity through radical scavenging, while Polysorbate 80 serves as a crucial emulsifier to stabilize the formulation.
Research
Clinical Evidence
Medium confidence5%
Transparency
Dusting Analysis
This ingredient is a complex ferment lysate filtrate, not typically prone to 'dusting' as a low-concentration active.
The Formula
Formulation
Stability
For optimal formulation integrity, it is recommended to incorporate this ingredient during the cooling phase, ensuring temperatures remain below 60°C (140°F).
Conflicts
- Highly anionic ingredients (e.g., certain thickeners like xanthan gum) may exhibit incompatibilities with the Leuconostoc Ferment Extract component.
Safety
Safety Profile
The CIR Expert Panel has concluded that Lactobacillus Ferment and its derivatives, including lysates and filtrates, are safe for cosmetic application, with reported use concentrations up to 5.6% in leave-on products. In vitro dermal and ocular irritation assays, along with human repeated insult patch tests (HRIPT) at 5%, predict a low risk of irritation. Formulators should be aware of its potential tyrosinase-inhibiting properties, which may lead to a skin lightening effect, though the CIR Panel has mitigated this concern.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This multifaceted ferment lysate offers significant soothing, barrier-enhancing, and antioxidant benefits, making it a valuable addition for diverse skin types, particularly those prone to redness and sensitivity, supported by a strong safety profile and formulation flexibility.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources